WormMine: RNAi WBRNAi00109112

• WormBase ID: WBRNAi00109112
• Genotype: mev-1(kn1)
• Phenotype Remark: "Likewise to the effects caused by RNAi for factors of UPRmt, the knockdown of proteins with relevance for UPR-ER such as XBP-1 (Fig. 6A), which controls a signaling pathway to prevent ER stress, or of genes activated in blocked UPR (abu) (Fig. 6B and C) excluded quercetin from exerting a survival-enhancing activity in the presence of glucose."
• Remark: (Figure 6B) abu-1 RNAi

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

2 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000024	abu-1	AC3.3	Caenorhabditis elegans
WBGene00004098	pqn-2	AC3.4	Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:AC3.3	AC3.3	1278	V: 10380426-10381649
CDS:AC3.4	AC3.4	1278	V: 10382478-10382531

0 Laboratories

1 Phenotype

Identifier	Name	Description
WBPhenotype:0001171	shortened life span	The duration of viability in the adult phase of the life-cycle is less than that of control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00044685

0 Strain