WormMine: Gene WBGene00007441

• WormBase Gene ID: WBGene00007441
• Gene Name: C08E8.5
• Sequence Name: C08E8.5
• Organism: Caenorhabditis elegans
• Automated Description: Predicted to enable translation elongation factor activity. Predicted to be involved in translational elongation.
• Biotype: SO:0001217
• Genetic Position: :±
• Length (nt): 171

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Synonyms

• Value: WBGene00007441

Genomics

1 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:C08E8.5.1	C08E8.5.1	171	V: 18359818-18359988

Other

1 CDSs

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:C08E8.5	C08E8.5	171	V: 18359818-18359988

0 RNAi Result

15 Allele

• gk963271
• gk963489
• gk963304
• gk963809
• gk963637
• gk962704
• gk963970
• gk963971
• gk320502
• gk470959
• gk517012
• gk588277
• gk692630
• gk262258
• WBVar01749473

1 Chromosome

• WormBase ID: V
• Organism: Caenorhabditis elegans
• Length (nt): 20924180

1 Chromosome Location

• Feature . Primary Identifier: WBGene00007441
• Start: 18359818
• End: 18359988
• Strand: -1

3 Data Sets

• WormBaseAcedbConverter
• GO Annotation data set
• C. elegans genomic annotations (GFF3 Gene)

1 Downstream Intergenic Region

• WormBase ID: intergenic_region_chrV_18359556..18359817
• Length (nt): 262
• Chromosome Location: V: 18359556-18359817
• Organism: Caenorhabditis elegans

17 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
adult vs dauer larva	Transcripts that showed differential expression in adult vs dauer lava in N2 animals at 20C.	N.A.	WBPaper00050488:adult_vs_dauer_regulated_N2_20C
	mRNAs that showed decreased expression in 1 cell mebryo comparing to in oocyte, according to RNAseq analysis.	Gaussian error propagation. As cutoff for the up-regulated genes authors used log2 fold change > 1 and P < 0.05 and as cutoff for the down-regulated genes authors used log2 fold change < -1 and P < 0.05.	WBPaper00045420:fertilization_downregulated_transcript
	Neuronally enriched transcripts according to a comparison of neuronal nuclei IP samples to total nuclei using isolation of nuclei from tagged specific cell types (INTACT) technology.	DESEQ2, fold change > 2 and FDR < 0.01.	WBPaper00062103:neuron_enriched
	Transcripts expressed in intestine, according to PAT-Seq analysis using Pges-1-GFP-3XFLAG mRNA tagging.	Cufflinks FPKM value >=1.	WBPaper00050990:intestine_expressed
	Transcripts unqiuely expressed in intestine, according to PAT-Seq analysis using Pges-1-GFP-3XFLAG mRNA tagging.	Cufflinks FPKM value >=1.	WBPaper00050990:intestine_enriched
	Transcripts that showed significantly decreased expression in whole animal day 1 N2 adults comparing to in whole animal day 8 N2 adults.	DESeq2, FDR < 0.05, fold change > 2.	WBPaper00066978:Day1Adult_vs_Day8Adult_downregulated_neuron
20C vs 25C	Transcripts that showed differential expression in 20C vs 25C in mir-34(gk437) animals at adult stage.	N.A.	WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
	Transcripts that showed differential expression in dauer mir-34(gk437) vs dauer mir-34(OverExpression) animals at 20C.	N.A.	WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
	Transcripts that showed differential expression in dauer N2 vs dauer mir-34(gk437) animals at 20C.	N.A.	WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
	Transcripts that showed significantly increased expression in PLM neuron cells comparing to in whole animal, according to dissected single neuron RNASeq analysis.	Fold change >= 4.	WBPaper00050344:PLM-neuron_enriched
	Genes that showed increased expression after exposure to 20uM HgCl2 for 24 hours.	Rosetta Resolver was used to identify differentially expressed genes using an error-weighted, 1-way ANOVA with a Bonferroni correction. A 2-fold change in expression, relative to untreated controls, and a p-value < 0.01 was required for a gene to qualify as significantly, differentially expressed.	WBPaper00044316:HgCl2_20uM_upregulated
	Genes that showed significantly increased expression in after 5 hours of 30ug/ml tunicamycin(TM) treatment comparing to control animals.	N.A.	WBPaper00045390:tunicamycin_upregulated
	Genes that showed significantly decreased expression level in rsr-2(RNAi) animals comparing to in gfp(RNAi) control.	Fold change > 1.2 or < 0.8.	WBPaper00042477:rsr-2(RNAi)_downregulated_TilingArray
	Transcripts that showed significantly increased expression in AFD neuron cells comparing to in whole animal, according to dissected single neuron RNASeq analysis.	Fold change >= 4.	WBPaper00050344:AFD-neuron_enriched
	Transcripts that showed significantly increased expression in ASER neuron cells comparing to in whole animal, according to dissected single neuron RNASeq analysis.	Fold change >= 4.	WBPaper00050344:ASER-neuron_enriched
	Single-cell RNA-Seq cell group 35_4 expressed in neuron.	scVI 0.6.0	WBPaper00065841:35_4
	Transcripts enriched in ASER according to single cell RNAseq.	Genes that pass the Bonferroni threshold for multiple comparisons (q < 0.05) are significantly enriched.	WBPaper00061651:ASER_enriched

2 Expression Patterns

• Primary Identifier: Expr1144174
• Pattern: Developmental gene expression time-course. Raw data can be downloaded from ftp://caltech.wormbase.org/pub/wormbase/datasets-published/hashimshony2015

• Primary Identifier: Expr1011090
• Pattern: Developmental gene expression time-course. Raw data can be downloaded from ftp://caltech.wormbase.org/pub/wormbase/datasets-published/levin2012

2 GO Annotation

0 Homologues

1 Locations

• Feature . Primary Identifier: WBGene00007441
• Start: 18359818
• End: 18359988
• Strand: -1

2 Ontology Annotations

0 Regulates Expr Cluster

1 Sequence

• Length: 171

1 Sequence Ontology Term

• Name: gene

0 Strains

1 Upstream Intergenic Region

• WormBase ID: intergenic_region_chrV_18359989..18361030
• Length (nt): 1042
• Chromosome Location: V: 18359989-18361030
• Organism: Caenorhabditis elegans