Predicted to enable heparosan-N-sulfate-glucuronate 5-epimerase activity. Predicted to be involved in heparan sulfate proteoglycan biosynthetic process. Is an ortholog of C. elegans hse-5. In C. elegans, hse-5 is involved in heparan sulfate proteoglycan biosynthetic process, enzymatic modification; regulation of cell migration; and regulation of growth.