WormMine: Gene WBGene00222208

• WormBase Gene ID: WBGene00222208
• Gene Name: Bma-pac-1
• Sequence Name: Bm1947
• Organism: Brugia malayi
• Automated Description: Predicted to be involved in signal transduction. Is an ortholog of C. elegans pac-1. In C. elegans, pac-1 is involved in protein localization; regulation of gastrulation; and small GTPase-mediated signal transduction.
• Biotype: SO:0001217
• Genetic Position: :±

1 Organism

• Name: Brugia malayi
• Taxon Id: 6279

0 Synonyms

Genomics

6 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:Bm1947d.1	Bm1947d.1		[unknown]
Transcript:Bm1947c.1	Bm1947c.1		[unknown]
Transcript:Bm1947b.1	Bm1947b.1		[unknown]
Transcript:Bm1947a.1	Bm1947a.1		[unknown]
Transcript:Bm1947f.1	Bm1947f.1		[unknown]
Transcript:Bm1947e.1	Bm1947e.1		[unknown]

Other

6 CDSs

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Bm1947f	Bm1947f		[unknown]
CDS:Bm1947a	Bm1947a		[unknown]
CDS:Bm1947d	Bm1947d		[unknown]
CDS:Bm1947e	Bm1947e		[unknown]
CDS:Bm1947b	Bm1947b		[unknown]
CDS:Bm1947c	Bm1947c		[unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

2 Data Sets

• WormBaseAcedbConverter
• GO Annotation data set

0 Downstream Intergenic Region

9 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Transcripts that showed significantly decreased expression in male B. malayi 120 days after infecting gerbils, comparing to female B. malayi 120 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:downregulated_M120_vs_F120
	Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP.	Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering.	WBPaper00045439:BM_Cluster_P1
	Transcripts that showed significantly increased expression in male B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:upregulated_M120_vs_M30
	Transcripts that showed significantly higher expression in L3 larva comparing to in adult.	edgeR v3.28. FDR < 0.05, fold change > 2.	WBPaper00061765:L3_vs_Adult_Upregulated
	Transcripts that showed significantly higher expression in L4 larva comparing to in adult.	edgeR v3.28. FDR < 0.05, fold change > 2.	WBPaper00061765:L4_vs_Adult_Upregulated
	Transcripts that showed significantly higher expression in L4 larva comparing to in microfilariae.	edgeR v3.28. FDR < 0.05, fold change > 2.	WBPaper00061765:L4_vs_Micro_Upregulated
	Proteins secreted by B.malayi at L3 larva stage, according to LC-MS-MS.	N.A.	WBPaper00050454:Secretome_protein
	Transcripts that showed significantly decreased expression in female B. malayi 120 days after infecting gerbils, comparing to 42 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:downregulated_F120_vs_F42
	Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP.	Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering.	WBPaper00045439:BM_Cluster_P6

0 Expression Patterns

1 GO Annotation

0 Homologues

0 Locations

1 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term

• Name: gene

0 Strains

0 Upstream Intergenic Region