WormMine: Gene WBGene00223961

• WormBase Gene ID: WBGene00223961
• Gene Name: Bma-fos-1
• Sequence Name: Bm3700
• Organism: Brugia malayi
• Automated Description: Predicted to enable DNA binding activity and DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is an ortholog of C. elegans fos-1. In C. elegans, fos-1 is involved in several processes, including determination of adult lifespan; negative regulation of stress response to copper ion; and regulation of gene expression.
• Biotype: SO:0001217
• Genetic Position: :±

1 Organism

• Name: Brugia malayi
• Taxon Id: 6279

0 Synonyms

Genomics

5 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:Bm3700b.1	Bm3700b.1		[unknown]
Transcript:Bm3700a.1	Bm3700a.1		[unknown]
Transcript:Bm3700d.1	Bm3700d.1		[unknown]
Transcript:Bm3700f.1	Bm3700f.1		[unknown]
Transcript:Bm3700e.1	Bm3700e.1		[unknown]

Other

5 CDSs

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Bm3700d	Bm3700d		[unknown]
CDS:Bm3700f	Bm3700f		[unknown]
CDS:Bm3700e	Bm3700e		[unknown]
CDS:Bm3700b	Bm3700b		[unknown]
CDS:Bm3700a	Bm3700a		[unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

2 Data Sets

• WormBaseAcedbConverter
• GO Annotation data set

0 Downstream Intergenic Region

6 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Transcripts that showed significantly higher expression in L3 larva comparing to in adult.	edgeR v3.28. FDR < 0.05, fold change > 2.	WBPaper00061765:L3_vs_Adult_Upregulated
	Transcripts that showed significantly increased expression in male B. malayi 120 days after infecting gerbils, comparing to 42 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:upregulated_M120_vs_M42
	Transcripts that showed significantly decreased expression in male B. malayi 30 days after infecting gerbils, comparing to female B. malayi 30 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:downregulated_M30_vs_F30
	Transcripts that showed significantly increased expression in female B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:upregulated_F120_vs_F30
	Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP.	Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering.	WBPaper00045439:BM_Cluster_P9
	Transcripts that showed significantly decreased expression in female B. malayi 30 days after infecting gerbils, comparing to L4 female B. malayi animals.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:downregulated_F30_vs_L4

0 Expression Patterns

4 GO Annotation

0 Homologues

0 Locations

4 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term

• Name: gene

0 Strains

0 Upstream Intergenic Region