WormMine: Gene WBGene00224320

• WormBase Gene ID: WBGene00224320
• Gene Name: Bma-haf-2
• Sequence Name: Bm4059
• Organism: Brugia malayi
• Automated Description: Predicted to enable ABC-type peptide transporter activity; ATP binding activity; and ATP hydrolysis activity. Predicted to be involved in peptide transport and transmembrane transport. Predicted to be located in lysosomal membrane. Is an ortholog of C. elegans haf-2. In C. elegans, haf-2 is involved in regulatory ncRNA-mediated post-transcriptional gene silencing.
• Biotype: SO:0001217
• Genetic Position: :±

1 Organism

• Name: Brugia malayi
• Taxon Id: 6279

0 Synonyms

Genomics

3 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:Bm4059b.1	Bm4059b.1		[unknown]
Transcript:Bm4059a.1	Bm4059a.1		[unknown]
Transcript:Bm4059a.2	Bm4059a.2		[unknown]

Other

2 CDSs

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Bm4059a	Bm4059a		[unknown]
CDS:Bm4059b	Bm4059b		[unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

2 Data Sets

• WormBaseAcedbConverter
• GO Annotation data set

0 Downstream Intergenic Region

5 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP.	Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering.	WBPaper00045439:BM_Cluster_P1
	Proteins that are enriched in digestive tract of adult female Brugia malayi.	Protein quantitation was determined by normalized spectral abundance.Proteins with NSAF enrichment values of 2 or greater were were considered enriched within that fraction.	WBPaper00048706:digestive-tract_enriched
	Transcripts that showed significantly decreased expression in male B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:downregulated_M120_vs_M30
	Transcripts that showed significantly increased expression in female B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:upregulated_F120_vs_F30
	Transcripts that showed significantly increased expression in male B. malayi 120 days after infecting gerbils, comparing to female B. malayi 120 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:upregulated_M120_vs_F120

0 Expression Patterns

9 GO Annotation

0 Homologues

0 Locations

9 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term

• Name: gene

0 Strains

0 Upstream Intergenic Region