WormMine: Gene WBGene00226485

• WormBase Gene ID: WBGene00226485
• Gene Name: Bma-nsun-1
• Sequence Name: Bm6224
• Organism: Brugia malayi
• Automated Description: Predicted to enable RNA binding activity; RNA methyltransferase activity; and S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in RNA methylation and RNA processing. Is an ortholog of C. elegans nsun-1. In C. elegans, nsun-1 is involved in several processes, including negative regulation of cellular response to heat; negative regulation of locomotion involved in locomotory behavior; and positive regulation of reproductive process.
• Biotype: SO:0001217
• Genetic Position: :±

1 Organism

• Name: Brugia malayi
• Taxon Id: 6279

0 Synonyms

Genomics

2 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:Bm6224a.1	Bm6224a.1		[unknown]
Transcript:Bm6224b.1	Bm6224b.1		[unknown]

Other

2 CDSs

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Bm6224b	Bm6224b		[unknown]
CDS:Bm6224a	Bm6224a		[unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

2 Data Sets

• WormBaseAcedbConverter
• GO Annotation data set

0 Downstream Intergenic Region

4 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Transcripts that showed significantly decreased expression in male B. malayi 120 days after infecting gerbils, comparing to female B. malayi 120 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:downregulated_M120_vs_F120
	Transcripts that showed significantly decreased expression in female B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:downregulated_F120_vs_F30
	Proteins secreted by B.malayi at L3 larva stage, according to LC-MS-MS.	N.A.	WBPaper00050454:Secretome_protein
	Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP.	Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering.	WBPaper00045439:BM_Cluster_P15

0 Expression Patterns

6 GO Annotation

0 Homologues

0 Locations

6 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term

• Name: gene

0 Strains

0 Upstream Intergenic Region