WormMine: Gene WBGene00227423

• WormBase Gene ID: WBGene00227423
• Gene Name: Bma-gcn-2
• Sequence Name: Bm7162
• Organism: Brugia malayi
• Automated Description: Predicted to enable ATP binding activity and eukaryotic translation initiation factor 2alpha kinase activity. Predicted to be involved in DNA damage checkpoint signaling. Is an ortholog of C. elegans gcn-2. In C. elegans, gcn-2 is involved in several processes, including determination of adult lifespan; positive regulation of protein modification process; and response to stress.
• Biotype: SO:0001217
• Genetic Position: :±

1 Organism

• Name: Brugia malayi
• Taxon Id: 6279

0 Synonyms

Genomics

5 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:Bm7162b.1	Bm7162b.1		[unknown]
Transcript:Bm7162a.1	Bm7162a.1		[unknown]
Transcript:Bm7162e.1	Bm7162e.1		[unknown]
Transcript:Bm7162d.1	Bm7162d.1		[unknown]
Transcript:Bm7162c.1	Bm7162c.1		[unknown]

Other

5 CDSs

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Bm7162d	Bm7162d		[unknown]
CDS:Bm7162c	Bm7162c		[unknown]
CDS:Bm7162b	Bm7162b		[unknown]
CDS:Bm7162a	Bm7162a		[unknown]
CDS:Bm7162e	Bm7162e		[unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

2 Data Sets

• WormBaseAcedbConverter
• GO Annotation data set

0 Downstream Intergenic Region

3 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Transcripts that showed significantly decreased expression in male B. malayi 120 days after infecting gerbils, comparing to female B. malayi 120 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:downregulated_M120_vs_F120
	Transcripts that showed significantly increased expression in male B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:upregulated_M120_vs_M30
	Transcripts that showed significantly increased expression in male B. malayi 120 days after infecting gerbils, comparing to 42 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:upregulated_M120_vs_M42

0 Expression Patterns

6 GO Annotation

0 Homologues

0 Locations

6 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term

• Name: gene

0 Strains

0 Upstream Intergenic Region