WormMine: Gene WBGene00227787

• WormBase Gene ID: WBGene00227787
• Gene Name: Bma-dbt-1
• Sequence Name: Bm7526
• Organism: Brugia malayi
• Automated Description: Predicted to enable acyltransferase activity. Is an ortholog of C. elegans dbt-1. In C. elegans, dbt-1 is involved in positive regulation of fatty acid biosynthetic process and positive regulation of multicellular organismal process.
• Biotype: SO:0001217
• Genetic Position: :±

1 Organism

• Name: Brugia malayi
• Taxon Id: 6279

0 Synonyms

Genomics

3 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:Bm7526b.1	Bm7526b.1		[unknown]
Transcript:Bm7526a.1	Bm7526a.1		[unknown]
Transcript:Bm7526c.1	Bm7526c.1		[unknown]

Other

3 CDSs

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Bm7526b	Bm7526b		[unknown]
CDS:Bm7526a	Bm7526a		[unknown]
CDS:Bm7526c	Bm7526c		[unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

2 Data Sets

• WormBaseAcedbConverter
• GO Annotation data set

0 Downstream Intergenic Region

4 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Transcripts that showed significantly lower expression in L3 larva comparing to in adult.	edgeR v3.28. FDR < 0.05, fold change > 2.	WBPaper00061765:L3_vs_Adult_Downregulated
	Transcripts that showed significantly higher expression in adult comparing to in microfilariae.	edgeR v3.28. FDR < 0.05, fold change > 2.	WBPaper00061765:Adult_vs_Micro_Upregulated
	Transcripts that showed significantly lower expression in L4 larva comparing to in adult.	edgeR v3.28. FDR < 0.05, fold change > 2.	WBPaper00061765:L4_vs_Adult_Downregulated
	Transcripts that showed significantly increased expression after 48 hours of 100nM ivermectin exposure.	Differential gene expression analysis between time points and drug concentrations was realized in edgeR (version 3.10.5) through the web interface provided by NetworkAnalyst. Significance was set as an experiment-wide false discovery rate (FDR) <0.20 (after the Benjamini-Hochberg method).	WBPaper00049974:ivermectin_100nM_48h_upregulated

0 Expression Patterns

1 GO Annotation

0 Homologues

0 Locations

1 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term

• Name: gene

0 Strains

0 Upstream Intergenic Region