WormMine: Gene WBGene00228585

• WormBase Gene ID: WBGene00228585
• Gene Name: Bma-cku-80
• Sequence Name: Bm8324
• Organism: Brugia malayi
• Automated Description: Predicted to enable DNA binding activity. Predicted to be involved in double-strand break repair via nonhomologous end joining. Is an ortholog of C. elegans cku-80. In C. elegans, cku-80 is involved in DNA repair.
• Biotype: SO:0001217
• Genetic Position: :±

1 Organism

• Name: Brugia malayi
• Taxon Id: 6279

0 Synonyms

Genomics

4 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:Bm8324b.1	Bm8324b.1		[unknown]
Transcript:Bm8324a.1	Bm8324a.1		[unknown]
Transcript:Bm8324d.1	Bm8324d.1		[unknown]
Transcript:Bm8324c.1	Bm8324c.1		[unknown]

Other

4 CDSs

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Bm8324b	Bm8324b		[unknown]
CDS:Bm8324c	Bm8324c		[unknown]
CDS:Bm8324a	Bm8324a		[unknown]
CDS:Bm8324d	Bm8324d		[unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

2 Data Sets

• WormBaseAcedbConverter
• GO Annotation data set

0 Downstream Intergenic Region

2 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Transcripts that showed significantly decreased expression in male B. malayi 120 days after infecting gerbils, comparing to female B. malayi 120 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:downregulated_M120_vs_F120
	Transcripts that showed significantly decreased expression after 5 days of 1uM ivermectin exposure.	Differential gene expression analysis between time points and drug concentrations was realized in edgeR (version 3.10.5) through the web interface provided by NetworkAnalyst. Significance was set as an experiment-wide false discovery rate (FDR) <0.20 (after the Benjamini-Hochberg method).	WBPaper00049974:ivermectin_1uM_5-day_downregulated

0 Expression Patterns

2 GO Annotation

0 Homologues

0 Locations

2 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term

• Name: gene

0 Strains

0 Upstream Intergenic Region