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Transcripts that showed significantly higher expression in adult comparing to in microfilariae. |
edgeR v3.28. FDR < 0.05, fold change > 2. |
WBPaper00061765:Adult_vs_Micro_Upregulated
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Transcripts that showed significantly increased expression after 48 hours of 1uM ivermectin exposure. |
Differential gene expression analysis between time points and drug concentrations was realized in edgeR (version 3.10.5) through the web interface provided by NetworkAnalyst. Significance was set as an experiment-wide false discovery rate (FDR) <0.20 (after the Benjamini-Hochberg method). |
WBPaper00049974:ivermectin_1uM_48h_upregulated
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Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP. |
Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering. |
WBPaper00045439:BM_Cluster_P16
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