WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

Disease Ontology : DOID:0060343 glucocorticoid-induced osteoporosis Disease Ontology

Namespace  disease_ontology Obsolete  false
Description  An osteoporosis caused by chronic glucocorticoid use. Glucocorticoids impair the replication, differentiation and function of osteoblasts and induce the apoptosis of mature osteoblasts and osteocytes; the also favor osteoclastogenesis leading to an increase in bone resorption.

1 Ontology

Name
Disease Ontology

9 Parents

Identifier Name Description
DOID:7 disease of anatomical entity A disease that manifests in a defined anatomical structure.
DOID:4 disease A disease is a disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism.
DOID:17 musculoskeletal system disease A disease of anatomical entity that occurs in the muscular and/or skeletal system.
DOID:0080001 bone disease A connective tissue disease that affects the structure or development of bone or causes an impairment of normal bone function.
DOID:65 connective tissue disease A musculoskeletal system disease that affects tissues such as skin, tendons, and cartilage.
DOID:0080005 bone remodeling disease A bone disease that results_in formation or resorption abnormalities located_in bone.
DOID:11476 osteoporosis A bone resorption disease characterized by decreased density of normally mineralized bone which results_in the thinning of bone tissue and decreased mechanical strength.
DOID:0060343 glucocorticoid-induced osteoporosis An osteoporosis caused by chronic glucocorticoid use. Glucocorticoids impair the replication, differentiation and function of osteoblasts and induce the apoptosis of mature osteoblasts and osteocytes; the also favor osteoclastogenesis leading to an increase in bone resorption.
DOID:0080011 bone resorption disease A bone remodeling disease that results in an abnormal decrease of bone density or mass.

8 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a DOID:11476 DOID:0060343
is_a DOID:7 DOID:0060343
is_a DOID:4 DOID:0060343
is_a DOID:17 DOID:0060343
is_a DOID:0080005 DOID:0060343
is_a DOID:65 DOID:0060343
is_a DOID:0080001 DOID:0060343
is_a DOID:0080011 DOID:0060343

1 Synonyms

Name Type
steroid-induced osteoporosis synonym