WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

Disease Ontology : DOID:0081076 blastic plasmacytoid dendritic cell neoplasm Disease Ontology

Namespace  disease_ontology Obsolete  false
Description  An acute leukemia that is derived from the precursors of plasmacytoid dendritic cells, with a high frequency of cutaneous and bone marrow involvement and leukemic dissemination. Skin lesions appearing on the arms, legs, face and neck are the most common BPDCN symptom. Other symptoms include low counts of healthy blood cells and swollen lymph nodes.

1 Ontology

Name
Disease Ontology

11 Parents

Identifier Name Description
DOID:0050686 organ system cancer A cancer that is classified based on the organ it starts in.
DOID:162 cancer A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.
DOID:7 disease of anatomical entity A disease that manifests in a defined anatomical structure.
DOID:14566 disease of cellular proliferation A disease that is characterized by abnormally rapid cell division.
DOID:4 disease A disease is a disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism.
DOID:74 hematopoietic system disease A disease of anatomical entity that has_material_basis_in hematopoietic cells.
DOID:2531 hematologic cancer An organ system cancer located in the hematological system that is characterized by uncontrolled cellular proliferation in blood, bone marrow and lymph nodes.
DOID:12603 acute leukemia A lymphoid leukemia that occurs when a hematopoietic stem cell undergoes malignant transformation into a primitive, undifferentiated cell with abnormal longevity producing large numbers of white blood cells to be produced and enter the blood stream.
DOID:1037 lymphoid leukemia A leukemia that has_material_basis_in a B-cell or T-cell lineage involving primarily the bone marrow and the peripheral blood.
DOID:1240 leukemia A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells.
DOID:0081076 blastic plasmacytoid dendritic cell neoplasm An acute leukemia that is derived from the precursors of plasmacytoid dendritic cells, with a high frequency of cutaneous and bone marrow involvement and leukemic dissemination. Skin lesions appearing on the arms, legs, face and neck are the most common BPDCN symptom. Other symptoms include low counts of healthy blood cells and swollen lymph nodes.

10 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a DOID:12603 DOID:0081076
is_a DOID:14566 DOID:0081076
is_a DOID:4 DOID:0081076
is_a DOID:1240 DOID:0081076
is_a DOID:2531 DOID:0081076
is_a DOID:7 DOID:0081076
is_a DOID:1037 DOID:0081076
is_a DOID:74 DOID:0081076
is_a DOID:0050686 DOID:0081076
is_a DOID:162 DOID:0081076

6 Synonyms

Name Type
Blastic Natural Killer Leukemia/Lymphoma synonym
Blastic NK-Cell Lymphoma synonym
CD4+/CD56+ Hematodermic Neoplasm synonym
natural killer (NK) cell leukemia/lymphoma synonym
Agranular CD4+ CD56+ Hematodermic Neoplasm/Tumor synonym
Agranular CD4+ Natural Killer Cell Leukemia synonym