WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

Disease Ontology : DOID:0081414 TFEB-rearranged renal cell carcinoma Disease Ontology

Namespace  disease_ontology Obsolete  false
Description  A renal cell carcinoma with MiT translocations that is characterized by the presence of the chromosomal translocation t(6;11) which fuses the TFEB transcription factor gene, located on chromosome 6, with the MALAT1 gene, located on chromosome 11.

1 Ontology

Name
Disease Ontology

15 Parents

Identifier Name Description
DOID:0050686 organ system cancer A cancer that is classified based on the organ it starts in.
DOID:162 cancer A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.
DOID:7 disease of anatomical entity A disease that manifests in a defined anatomical structure.
DOID:14566 disease of cellular proliferation A disease that is characterized by abnormally rapid cell division.
DOID:4 disease A disease is a disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism.
DOID:18 urinary system disease A disease of anatomical entity that is located_in kidney, ureter, bladder and urethra.
DOID:557 kidney disease A urinary system disease that is located_in the kidney.
DOID:305 carcinoma A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.
DOID:263 kidney cancer A urinary system cancer that is located_in the kidney.
DOID:0050687 cell type cancer A cancer that is classified by the type of cell from which it is derived.
DOID:4450 renal cell carcinoma A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.
DOID:4451 renal carcinoma A kidney cancer that derives_from the lining of the proximal convoluted tubule (the very small tubes in the kidney that filter the blood and remove waste products).
DOID:3996 urinary system cancer An organ system cancer that is located_in the kidneys, ureteres, bladder or urethra.
DOID:0081413 renal cell carcinoma with MiT translocations A renal cell carcinoma that is characterized by papillary, alveolar and nested growth patterns with clear and eosinophilic cells and that is associated with translocations/gene fusions involving members of the MiT family of transcription factors.
DOID:0081414 TFEB-rearranged renal cell carcinoma A renal cell carcinoma with MiT translocations that is characterized by the presence of the chromosomal translocation t(6;11) which fuses the TFEB transcription factor gene, located on chromosome 6, with the MALAT1 gene, located on chromosome 11.

14 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a DOID:0081413 DOID:0081414
is_a DOID:0050686 DOID:0081414
is_a DOID:4451 DOID:0081414
is_a DOID:4450 DOID:0081414
is_a DOID:18 DOID:0081414
is_a DOID:263 DOID:0081414
is_a DOID:3996 DOID:0081414
is_a DOID:162 DOID:0081414
is_a DOID:14566 DOID:0081414
is_a DOID:557 DOID:0081414
is_a DOID:0050687 DOID:0081414
is_a DOID:4 DOID:0081414
is_a DOID:305 DOID:0081414
is_a DOID:7 DOID:0081414

4 Synonyms

Name Type
Renal Cell Carcinoma with t(6;11);(p21;q12); MALAT1-TFEB synonym
Renal Cell Carcinoma with t(6;11);(p21;q12); MALAT1::TFEB synonym
t(6;11) Renal Cell Carcinoma synonym
t(6;11);(p21;q12) Renal Cell Carcinoma synonym