WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

Disease Ontology : DOID:0081415 TFE3-rearranged renal cell carcinoma Disease Ontology

Namespace  disease_ontology Obsolete  false
Description  A renal cell carcinoma with MiT translocations that is characterized by the presence of different translocations involving the chromosome Xp11.2 and that result in the creation of gene fusions involving the TFE3 gene.

1 Ontology

Name
Disease Ontology

15 Parents

Identifier Name Description
DOID:0050686 organ system cancer A cancer that is classified based on the organ it starts in.
DOID:162 cancer A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.
DOID:7 disease of anatomical entity A disease that manifests in a defined anatomical structure.
DOID:14566 disease of cellular proliferation A disease that is characterized by abnormally rapid cell division.
DOID:4 disease A disease is a disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism.
DOID:18 urinary system disease A disease of anatomical entity that is located_in kidney, ureter, bladder and urethra.
DOID:557 kidney disease A urinary system disease that is located_in the kidney.
DOID:305 carcinoma A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.
DOID:263 kidney cancer A urinary system cancer that is located_in the kidney.
DOID:0050687 cell type cancer A cancer that is classified by the type of cell from which it is derived.
DOID:4450 renal cell carcinoma A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.
DOID:4451 renal carcinoma A kidney cancer that derives_from the lining of the proximal convoluted tubule (the very small tubes in the kidney that filter the blood and remove waste products).
DOID:3996 urinary system cancer An organ system cancer that is located_in the kidneys, ureteres, bladder or urethra.
DOID:0081413 renal cell carcinoma with MiT translocations A renal cell carcinoma that is characterized by papillary, alveolar and nested growth patterns with clear and eosinophilic cells and that is associated with translocations/gene fusions involving members of the MiT family of transcription factors.
DOID:0081415 TFE3-rearranged renal cell carcinoma A renal cell carcinoma with MiT translocations that is characterized by the presence of different translocations involving the chromosome Xp11.2 and that result in the creation of gene fusions involving the TFE3 gene.

14 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a DOID:0081413 DOID:0081415
is_a DOID:4451 DOID:0081415
is_a DOID:4450 DOID:0081415
is_a DOID:18 DOID:0081415
is_a DOID:3996 DOID:0081415
is_a DOID:162 DOID:0081415
is_a DOID:263 DOID:0081415
is_a DOID:0050687 DOID:0081415
is_a DOID:4 DOID:0081415
is_a DOID:14566 DOID:0081415
is_a DOID:0050686 DOID:0081415
is_a DOID:305 DOID:0081415
is_a DOID:557 DOID:0081415
is_a DOID:7 DOID:0081415

2 Synonyms

Name Type
Renal Cell Carcinoma Associated with Xp11.2 Translocations/TFE3 Gene Fusions synonym
Xp11 Translocation Renal Cell Carcinoma synonym