WormMine

WS296

Intermine data mining platform for C. elegans and related nematodes

Disease Ontology : DOID:0111734 aminoglycoside-induced deafness Disease Ontology

Namespace  disease_ontology Obsolete  false
Description  A drug-induced hearing loss characterized by hearing loss induced by therapeutic doses of aminoglycoside antibiotics that has_material_basis_in mutation in the mitochondrial genes MTRNR1 or MTCO1 in combination with homozygous mutation in TRMU on chromosome 22q13.31.

1 Ontology

Name
Disease Ontology

8 Parents

Identifier Name Description
DOID:7 disease of anatomical entity A disease that manifests in a defined anatomical structure.
DOID:4 disease A disease is a disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism.
DOID:863 nervous system disease A disease of anatomical entity that is located_in the central nervous system or located_in the peripheral nervous system.
DOID:0050155 sensory system disease A nervous system disease which is located in a part of the nervous system responsible for processing sensory information that consists of sensory receptors, neural pathways, and parts of the brain involved in sensory perception. Commonly recognized sensory systems are those for vision, hearing, somatic sensation (touch), taste and olfaction (smell).
DOID:2742 auditory system disease A sensory system disease that is characterized by auditory dysfunction located_in the auditory system.
DOID:0050563 nonsyndromic deafness An auditory system disease that is associated with permanent hearing loss caused by damage to structures in the inner ear and/or the middle ear, which is not associated with other signs and symptoms.
DOID:0070310 drug-induced hearing loss A nonsyndromic deafness that is characterized by cochlear or vestibular dysfunction resulting in loss of hearing caused by drug ototoxicity.
DOID:0111734 aminoglycoside-induced deafness A drug-induced hearing loss characterized by hearing loss induced by therapeutic doses of aminoglycoside antibiotics that has_material_basis_in mutation in the mitochondrial genes MTRNR1 or MTCO1 in combination with homozygous mutation in TRMU on chromosome 22q13.31.

7 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a DOID:0070310 DOID:0111734
is_a DOID:7 DOID:0111734
is_a DOID:4 DOID:0111734
is_a DOID:0050563 DOID:0111734
is_a DOID:863 DOID:0111734
is_a DOID:0050155 DOID:0111734
is_a DOID:2742 DOID:0111734

2 Synonyms

Name Type
streptomycin ototoxicity synonym
streptomycin-induced deafness synonym