WormMine

WS296

Intermine data mining platform for C. elegans and related nematodes

Disease Ontology : DOID:12217 Lewy body dementia Disease Ontology

Namespace  disease_ontology Obsolete  false
Description  A dementia that is characterized by the development of abnormal proteinaceous (alpha-synuclein) cytoplasmic inclusions, called Lewy bodies, throughout the brain that results in progressive decline in mental abilities that has_material_basis_in accumulation of alpha-synuclein, SCNA, (protein). The causal mutation might be in SCNA or SCNB or some other gene(s) but the end result is always accumulation of SCNA in Lewy bodies.

1 Ontology

Name
Disease Ontology

5 Parents

Identifier Name Description
DOID:4 disease A disease is a disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism.
DOID:150 disease of mental health A disease that involves a psychological or behavioral pattern generally associated with subjective distress or disability that occurs in an individual, and which are not a part of normal development or culture.
DOID:1561 cognitive disorder A disease of mental health that affects cognitive functions including memory processing, perception and problem solving.
DOID:1307 dementia A cognitive disorder resulting from a loss of brain function affecting memory, thinking, language, judgement and behavior.
DOID:12217 Lewy body dementia A dementia that is characterized by the development of abnormal proteinaceous (alpha-synuclein) cytoplasmic inclusions, called Lewy bodies, throughout the brain that results in progressive decline in mental abilities that has_material_basis_in accumulation of alpha-synuclein, SCNA, (protein). The causal mutation might be in SCNA or SCNB or some other gene(s) but the end result is always accumulation of SCNA in Lewy bodies.

4 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a DOID:1307 DOID:12217
is_a DOID:1561 DOID:12217
is_a DOID:150 DOID:12217
is_a DOID:4 DOID:12217

4 Synonyms

Name Type
Dementia with Lewy bodies synonym
Diffuse Lewy body disease synonym
Lewy body disease synonym
Senile dementia of the Lewy body type synonym