WormMine: Gene WBGene00226771

• WormBase Gene ID: WBGene00226771
• Gene Name: Bma-crh-1
• Sequence Name: Bm6510
• Organism: Brugia malayi
• Automated Description: Predicted to enable DNA binding activity and DNA-binding transcription factor activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans crh-1. In C. elegans, crh-1 is involved in determination of adult lifespan; intracellular signal transduction; and regulation of transcription by RNA polymerase II.
• Biotype: SO:0001217
• Genetic Position: :±

1 Organism

• Name: Brugia malayi
• Taxon Id: 6279

0 Synonyms

Genomics

2 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:Bm6510a.1	Bm6510a.1		[unknown]
Transcript:Bm6510b.1	Bm6510b.1		[unknown]

Other

2 CDSs

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Bm6510b	Bm6510b		[unknown]
CDS:Bm6510a	Bm6510a		[unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

2 Data Sets

• WormBaseAcedbConverter
• GO Annotation data set

0 Downstream Intergenic Region

7 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Transcripts that showed significantly increased expression in male B. malayi 120 days after infecting gerbils, comparing to 42 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:upregulated_M120_vs_M42
	Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP.	Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering.	WBPaper00045439:BM_Cluster_P13
	Transcripts that showed significantly increased expression in male B. malayi 42 days after infecting gerbils, comparing to 30 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:upregulated_M42_vs_M30
	Transcripts that showed significantly decreased expression in male B. malayi 30 days after infecting gerbils, comparing to L4 male B. malayi animals.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:downregulated_M30_vs_L4
	Transcripts that showed significantly lower expression in L4 larva comparing to in adult.	edgeR v3.28. FDR < 0.05, fold change > 2.	WBPaper00061765:L4_vs_Adult_Downregulated
	Transcripts that showed significantly increased expression in female B. malayi 30 days after infecting gerbils, comparing to L4 female B. malayi animals.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:upregulated_F30_vs_L4
	Transcripts that showed significantly increased expression in parasites exposed to 20-hydroxyecdysone.	edgeR was used to analyze the data using the counts generated for the four samples with Cuffdiff.	WBPaper00049261:20-hydroxyecdysone_upregulated_RNAseq

0 Expression Patterns

4 GO Annotation

0 Homologues

0 Locations

4 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term