WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

Gene :

WormBase Gene ID  ? WBGene00227876 Gene Name  Bma-let-23
Sequence Name  ? Bm7615 Organism  Brugia malayi
Automated Description  Predicted to enable protein tyrosine kinase activity. Is an ortholog of C. elegans let-23. In C. elegans, let-23 is involved in several processes, including determination of adult lifespan; positive regulation of vulval development; and reproductive structure development. Biotype  SO:0001217
Genetic Position 
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1 Organism

Name Taxon Id
Brugia malayi 6279

0 Synonyms

Genomics

1 Transcripts

WormMine ID Sequence Name Length (nt) Chromosome Location
Transcript:Bm7615.1 Bm7615.1   [unknown]
 

Other

1 CDSs

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:Bm7615 Bm7615   [unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

2 Data Sets

Name URL
WormBaseAcedbConverter  
GO Annotation data set  

0 Downstream Intergenic Region

7 Expression Clusters

Regulated By Treatment Description Algorithm Primary Identifier
  Transcripts that showed significantly lower expression in adult comparing to in microfilariae. edgeR v3.28. FDR < 0.05, fold change > 2. WBPaper00061765:Adult_vs_Micro_Downregulated
  Transcripts that showed significantly decreased expression in male B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:downregulated_M120_vs_M30
  Transcripts that showed significantly decreased expression in male B. malayi 30 days after infecting gerbils, comparing to female B. malayi 30 days after infecting gerbils. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:downregulated_M30_vs_F30
  Transcripts that showed significantly increased expression in female B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:upregulated_F120_vs_F30
  Transcripts that showed significantly lower expression in L4 larva comparing to in microfilariae. edgeR v3.28. FDR < 0.05, fold change > 2. WBPaper00061765:L4_vs_Micro_Downregulated
  Transcripts that showed significantly increased expression in male B. malayi 120 days after infecting gerbils, comparing to female B. malayi 120 days after infecting gerbils. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:upregulated_M120_vs_F120
  Transcripts that showed significantly decreased expression at infective lava stage 3 (iL3) (from mosquitoes), comparing to L4 worms. Differential gene expression analysis was performed using both DESeq and EdgeR, and the overlapping genes with FDR<0.01 were retained. WBPaper00059852:B.malayi_iL3_stage_downregulated_vs_L4

0 Expression Patterns

3 GO Annotation

Annotation Extension Qualifier
  involved_in
  enables
  enables

0 Homologues

0 Locations

3 Ontology Annotations

Annotation Extension Qualifier
  involved_in
  enables
  enables

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term