WormMine: Gene WBGene00235273

• WormBase Gene ID: WBGene00235273
• Gene Name: T11F8.12
• Sequence Name: T11F8.12
• Organism: Caenorhabditis elegans
• Automated Description: Predicted to be located in membrane.
• Biotype: SO:0001217
• Genetic Position: :±
• Length (nt): 1774

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Synonyms

• Value: WBGene00235273

Genomics

1 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:T11F8.12.1	T11F8.12.1	485	IV: 5480558-5482331

Other

1 CDSs

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:T11F8.12	T11F8.12	402	IV: 5480607-5480743

0 RNAi Result

22 Allele

• otn9998
• gk964500
• gk963722
• gk963417
• gk963150
• gk963375
• gk963416
• gk481505
• gk868464
• gk502166
• gk522349
• gk325258
• gk460471
• gk787270
• gk694842
• gk953708
• gk202002
• gk202004
• gk202003
• WBVar01727723
• otn3191
• WBVar01923368

1 Chromosome

• WormBase ID: IV
• Organism: Caenorhabditis elegans
• Length (nt): 17493829

1 Chromosome Location

• Feature . Primary Identifier: WBGene00235273
• Start: 5480558
• End: 5482331
• Strand: -1

3 Data Sets

• WormBaseAcedbConverter
• GO Annotation data set
• C. elegans genomic annotations (GFF3 Gene)

0 Downstream Intergenic Region

19 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Transcripts of coding genes that showed significantly decreased expression in muscle.	DESeq2 (version 1.24.0). Transcripts with a false-discovery rate adjusted p-value less than 0.05 were considered significantly differentially expressed.	WBPaper00062325:muscle_depleted_coding-RNA
	Transcripts that showed significantly increased expression after animals were treated with 50uM Rifampicin and 250uM Allantoin from day 1 to day 3 adult hermaphradite.	DESeq2(v1.14.1), fold change > 2, p-value < 0.05	WBPaper00055354:Rifampicin-Allantoin_upregulated
	Transcripts that showed significantly altered expression at URX, AQR, and PQR neurons in camt-1(ok515) animals comparing to in wild type AX1888-1 strain.	RNA-seq data were mapped using PRAGUI - a Python 3-based pipeline for RNA-seq data analysis.	WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
	Transcripts that showed significantly increased expression in hda-2(ok1479) comparing to in N2 animals.	DESeq2 (version 1.28.1), FDR < 0.01, fold change > 2.	WBPaper00062159:hda-2(ok1479)_upregulated
Acidic Environment: PH 4.33 vs. PH 6.33.	Transcripts that showed significantly increased expression after 3 hours of exposure to acidic environment (PH 4.33), comparing to control animals exposed to PH 6.33 environment.	DESeq2 (1.16.1). The Benjamini and Hochberg's approach was used to adjust the resulting P-values to control the false discovery rate. Corrected value of P < 0.05 and fold change > 2 were set as the threshold for significantly differential expression.	WBPaper00060434:pH4.33_vs_pH6.33_uprgulated
	Top 300 transcripts enriched in g1AL, g1AR according to single cell RNAseq.	Top 300 enriched transcripts were determined by log2.ratio of the tpm in the cell type vs the tpm in the other cells * the log2 of the cell.type tpm.	WBPaper00061340:g1A
Temperature Shift: 25C vs 15C for 16 hours at L4 larva stage.	Transcripts that showed significantly decreased expression in AFD neurons comparing to in whole animals.	DESeq2, fold change > 2, FDR < 0.05.	WBPaper00065158:AFD_depleted
	Transcripts that showed significantly increased expression in elli-1(sam-3) comparing to in N2 animals, accordingto tiling array analysis.	Fold change > 1.2, q-value < 0.05.	WBPaper00050743:elli-1(sam-3)_upregulated
	Transcripts that showed significantly increased expression in PLM neuron cells comparing to in whole animal, according to dissected single neuron RNASeq analysis.	Fold change >= 4.	WBPaper00050344:PLM-neuron_enriched
	Transcripts that showed significantly increased expression in PVD neurons isolated from TV22833 wyIs840(ser2prom3::daf-12a(rh273)::gfpnovo2, Pmyo-2::gfp); wyIs592(ser2prom3::myr-gfp), comparing to in PVD neurons isolated from animals that only expressed wyIs592.	Cufflinks 2.2.1	WBPaper00058678:DAF-12_upregulated_PVD
Starvation 48 hours at L1 arrest	Transcripts that showed significantly decreased expression in starved N2 animals (48 hours at L1 arrest)	Fold change > 2.	WBPaper00064005:starvation_downregulated_N2_mRNA
	Single-cell RNA-Seq cell group 78_0 expressed in gland.	scVI 0.6.0	WBPaper00065841:78_0
	Top 300 transcripts enriched in g1AL, g1AR, g1P according to single cell RNAseq.	Top 300 enriched transcripts were determined by log2.ratio of the tpm in the cell type vs the tpm in the other cells * the log2 of the cell.type tpm.	WBPaper00061340:g1A_g1P
	Top 300 transcripts enriched in g1P according to single cell RNAseq.	Top 300 enriched transcripts were determined by log2.ratio of the tpm in the cell type vs the tpm in the other cells * the log2 of the cell.type tpm.	WBPaper00061340:g1P
	Single-cell RNA-Seq cell group 41_0 expressed in gland.	scVI 0.6.0	WBPaper00065841:41_0
	Single-cell RNA-Seq cell group 41_1 expressed in epithelium.	scVI 0.6.0	WBPaper00065841:41_1
	Single-cell RNA-Seq cell group 41_2 expressed in epithelium.	scVI 0.6.0	WBPaper00065841:41_2
	Transcripts that showed significantly increased expression in ASER neuron cells comparing to in whole animal, according to dissected single neuron RNASeq analysis.	Fold change >= 4.	WBPaper00050344:ASER-neuron_enriched
	Top 300 transcripts enriched in g2L, g2R according to single cell RNAseq.	Top 300 enriched transcripts were determined by log2.ratio of the tpm in the cell type vs the tpm in the other cells * the log2 of the cell.type tpm.	WBPaper00061340:g2

2 Expression Patterns

• Primary Identifier: Expr2006101
• Pattern: Single cell embryonic expression. Only cell types with an expression fraction of greater 0.2 of the maximum expressed fraction are labeled (Full data can be downloaded from http://caltech.wormbase.org/pub/wormbase/datasets-published/packer2019/). The colors represent the broad cell class to which the cell type has been assigned. The size of the point is proportional to the log2 of the numbers of cells in the dataset of that cell type. Interactive visualizations are available as a web app (https://cello.shinyapps.io/celegans/) and can also be installed as an R package (https://github.com/qinzhu/VisCello.celegans).

• Primary Identifier: Expr2024315
• Pattern: Single cell embryonic expression. Only cell types with an expression fraction of greater 0.2 of the maximum expressed fraction are labeled (Full data can be downloaded from http://caltech.wormbase.org/pub/wormbase/datasets-published/packer2019/). The colors represent the broad cell class to which the cell type has been assigned. The size of the point is proportional to the log2 of the numbers of cells in the dataset of that cell type. Interactive visualizations are available as a web app (https://cello.shinyapps.io/celegans/) and can also be installed as an R package (https://github.com/qinzhu/VisCello.celegans).

1 GO Annotation

0 Homologues

1 Locations

• Feature . Primary Identifier: WBGene00235273
• Start: 5480558
• End: 5482331
• Strand: -1

1 Ontology Annotations

0 Regulates Expr Cluster

1 Sequence

• Length: 1774

1 Sequence Ontology Term