WormMine: Gene WBGene00206514

• WormBase Gene ID: WBGene00206514
• Gene Name: R05G9.5
• Sequence Name: R05G9.5
• Organism: Caenorhabditis elegans
• Automated Description: Enriched in GLR and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including etr-1; xrep-4; and glp-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies.
• Biotype: SO:0001217
• Genetic Position: :±
• Length (nt): 1143

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Synonyms

• Value: WBGene00206514

Genomics

1 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:R05G9.5.1	R05G9.5.1	576	II: 6499119-6500261

Other

1 CDSs

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:R05G9.5	R05G9.5	576	II: 6499119-6499251

1 RNAi Result

• WBRNAi00051332

11 Allele

• gk963801
• gk963053
• gk962245
• WBVar01240493
• gk561137
• gk450322
• gk407330
• gk748762
• gk915591
• gk791627
• gk490052

1 Chromosome

• WormBase ID: II
• Organism: Caenorhabditis elegans
• Length (nt): 15279421

1 Chromosome Location

• Feature . Primary Identifier: WBGene00206514
• Start: 6499119
• End: 6500261
• Strand: -1

2 Data Sets

• WormBaseAcedbConverter
• C. elegans genomic annotations (GFF3 Gene)

0 Downstream Intergenic Region

18 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Transcripts that showed significantly increased expression in L1 neural cells comparing to in adult neural cells.	DESeq2 (v1.18.1) fold change > 2, P-adj<0.05, using BenjaminiHochberg correction.	WBPaper00060811:L1_vs_adult_upregulated_neural
	Transcripts of coding genes that showed significantly decreased expression in muscle.	DESeq2 (version 1.24.0). Transcripts with a false-discovery rate adjusted p-value less than 0.05 were considered significantly differentially expressed.	WBPaper00062325:muscle_depleted_coding-RNA
	Neuronally enriched transcripts according to a comparison of neuronal nuclei IP samples to total nuclei using isolation of nuclei from tagged specific cell types (INTACT) technology.	DESEQ2, fold change > 2 and FDR < 0.01.	WBPaper00062103:neuron_enriched
	Transcripts that showed significantly increased expression glp-1(e2141); TU3401 animals comparing to in TU3401 animals.	Fold change > 2, FDR < 0.01.	WBPaper00065993:glp-1(e2141)_upregulated
	Transcripts that showed significantly increased expression in xrep-4(lax137).	DESeq2. Genes were selected if their p value < 0.01.	WBPaper00066062:xrep-4(lax137)_upregulated
	Transcripts that showed significantly increased expression in ilc-17.1(syb5296) comparing to in N2 animals at L4 larva stage.	DESeq2, fold change > 2, FDR < 0.05.	WBPaper00066594:ilc-17.1(syb5296)_upregulated
	Transcripts that showed significantly increased expression in hda-2(ok1479) comparing to in N2 animals.	DESeq2 (version 1.28.1), FDR < 0.01, fold change > 2.	WBPaper00062159:hda-2(ok1479)_upregulated
Bacteria: S.maltophilia	Transcriptions that showed signigicantly alted expression in animals treated with pathogenic S.maltophilia strains for 12 hours, comparing to animals treated with non-pathogenic	Transcripts were considered significantly differentially expressed between treatments if the fold change > 2 and the false discovery rate (FDR) - adjusted p-value < 0.05.	WBPaper00059839:S.maltophilia_regulated
Hypoxia: 7% oxygen.	Transcripts that showed significantly increased expression at animals treated with 7% oxygen, comparing to animals grown at 21% oxygen.	Fold change > 2, p-value < 0.05.	WBPaper00060661:hypoxia_upregulated
25C vs. 20C	Transcripts that showed significantly decreased expression in 1-day post L4 adult hermaphrodite N2 grown at 25C, comparing to in N2 animals grown at 20C.	CuffDiff, fold change > 2.	WBPaper00065096:25C_vs_20C_downregulated
	Transcripts that showed significantly decreased expression in 10-days post L4 adult hermaphrodite N2 grown at 20C, comparing to in 1-day post L4 adult hermaphrodite N2 animals grown at 20C.	CuffDiff, fold change > 2.	WBPaper00065096:Day10_vs_Day1_downregulated
	Transcripts that showed significantly increased expression in sensory neuron (labeled by iaIs25[Pgcy-37::GFP + unc-119(+)]) comparing to in whole worm.	Fold change > 2, p-value < 0.05.	WBPaper00060661:sensory-neuron_enriched
	Transcripts the showed altered expression after auxin induced sacy-1 depletion (24 hours of 2mM auxin treatment at 20C starting from young adult hermaphrodite stage).	DESeq2	WBPaper00059334:sacy-1(depletion)_regulated
	Transcripts that showed significantly increased expression in animals with pan-neuronal expression of both human amyloid beta (snb-1p-Amyloid-beta(1-42) + mtl-2p-GFP) and human alpha-Synuclein(A53T) (aex-3p-alpha-syn (A53T)), comparing to in N2 animals.	edgeR p-value < 0.01 and fold change > 4.	WBPaper00061613:human-amyloid-beta_alpha-Synuclein(A53T)_upregulated
	Genes that showed significantly increased expression after exposure to 1mg/L MWCNTs from L1 larva to young adult.	Transcripts with false discovery rate-corrected p-values < 0.05 and fold change > 2 were defined as differentially expressed.	WBPaper00049377:MWCNT_upregulated
	Single-cell RNA-Seq cell group 75_0 expressed in neuron.	scVI 0.6.0	WBPaper00065841:75_0
	Single-cell RNA-Seq cell group 140_0 expressed in neuron.	scVI 0.6.0	WBPaper00065841:140_0
	Single-cell RNA-Seq cell group 119_0 expressed in mesoderm.	scVI 0.6.0	WBPaper00065841:119_0

1 Expression Patterns

• Primary Identifier: Expr1155026
• Pattern: Developmental gene expression time-course. Raw data can be downloaded from ftp://caltech.wormbase.org/pub/wormbase/datasets-published/hashimshony2015

0 GO Annotation

0 Homologues

1 Locations

• Feature . Primary Identifier: WBGene00206514
• Start: 6499119
• End: 6500261
• Strand: -1

0 Ontology Annotations

0 Regulates Expr Cluster

1 Sequence

• Length: 1143

1 Sequence Ontology Term