WormMine: Gene WBGene00219949

• WormBase Gene ID: WBGene00219949
• Gene Name: F44E5.16
• Sequence Name: F44E5.16
• Organism: Caenorhabditis elegans
• Automated Description: Enriched in AFD based on RNA-seq studies. Is affected by several genes including cua-1; ptl-1; and ptrn-1 based on RNA-seq and microarray studies.
• Biotype: SO:0001263
• Genetic Position: :±
• Length (nt): 135

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Synonyms

• Value: WBGene00219949

Genomics

1 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:F44E5.16	F44E5.16	135	II: 11756785-11756919

Other

0 CDSs

0 RNAi Result

9 Allele

• gk963801
• gk963053
• gk962684
• gk963539
• WBVar01538742
• WBVar02089246
• gk942321
• gk641905
• gk657811

1 Chromosome

• WormBase ID: II
• Organism: Caenorhabditis elegans
• Length (nt): 15279421

1 Chromosome Location

• Feature . Primary Identifier: WBGene00219949
• Start: 11756785
• End: 11756919
• Strand: 1

2 Data Sets

• WormBaseAcedbConverter
• C. elegans genomic annotations (GFF3 Gene)

1 Downstream Intergenic Region

• WormBase ID: intergenic_region_chrII_11756920..11757106
• Length (nt): 187
• Chromosome Location: II: 11756920-11757106
• Organism: Caenorhabditis elegans

22 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
25C vs. 20C	Transcripts that showed significantly increased expression in 1-day post L4 adult hermaphrodite N2 grown at 25C, comparing to in N2 animals grown at 20C.	CuffDiff, fold change > 2.	WBPaper00065096:25C_vs_20C_upregulated
	Transcripts that showed significantly increased expression in 10-days post L4 adult hermaphrodite N2 grown at 20C, comparing to in 1-day post L4 adult hermaphrodite N2 animals grown at 20C.	CuffDiff, fold change > 2.	WBPaper00065096:Day10_vs_Day1_upregulated
	Transcripts that showed significantly increased expression in set-2(tm1630) animals at embryo stage, comparing to in N2 animals.	DESeq2 (v2.1.8.3) was used to determine DE genes and to generate principal component and scatter plots. DE genes with FDR < 0.05 were analysed using g:Profiler with Bonferroni correction.	WBPaper00060014:set-2(tm1630)_upregulated
Dietary restriction	Transcripts that showed significantly increased expression after N2 animals were under dietary restriction (DR, OP50 OD = 0.1) from 3-day post L4 till 6-day post L4 adult hermaphrodite stage, comparing to under ad libtum (AL, OP50 OD = 3) condition.	Bioconductor package edgeR, p < 0.05.	WBPaper00056443:DietaryRestriction_upregulated
	Transcripts that interact with 3xFLAG-DLC-1 as identified by immunoprecipitation followed by RNA sequencing.	DESeq2, fold change > 2,, p-value < 0.01	WBPaper00055334:DLC-1_interacting
Temperature Shift: 25C vs 15C for 16 hours at L4 larva stage.	Transcripts that showed significantly increased expression in AFD neurons comparing to in whole animals.	DESeq2, fold change > 2, FDR < 0.05.	WBPaper00065158:AFD_enriched
	Transcripts that showed significantly decreased expression in ogt-1(ok1474) neuronal cells isolated by FACs comparing to in FACs isolated neuronal cells from wild type.	DESeq2, fold change > 2, FDR < 0.05.	WBPaper00066485:ogt-1(ok1474)_downregulated_neuron
	Transcripts that showed significantly decreased expression in daf-2(e1370) comparing to in N2.	Student's t-test, fold change > 2, p-value < 0.05.	WBPaper00055386:daf-2(e1370)_downregulated
	Transcripts that showed significantly decreased expression in daf-16(mu86);daf-2(e1370) neurons comparing to in daf-2(e1370) neurons at day 8adult stage.	DESeq2, FDR < 0.05, fold change > 2.	WBPaper00066978:daf-16(mu86)_downregulated_neuron
	Transcripts the showed altered expression after auxin induced sacy-1 depletion (24 hours of 2mM auxin treatment at 20C starting from young adult hermaphrodite stage).	DESeq2	WBPaper00059334:sacy-1(depletion)_regulated
	Transcripts that showed significantly decreased expression in mrps-5(RNAi) comparing to in control animals.	Fold change > 4, p-value < 0.01	WBPaper00056330:mrps-5(RNAi)_downregulated
	Transcripts that showed significantly increased expression in ptl-1(ok621) comparing to in N2	DESeq2 1.14.1, fold change > 1.5, p-value < 0.01.	WBPaper00056039:ptl-1(ok621)_upregulated
	Transcripts that showed significantly increased expression in hda-6(ok3203) comparing to in N2	DESeq2 1.14.1, fold change > 1.5, p-value < 0.01.	WBPaper00056039:hda-6(ok3203)_upregulated
Temperature Shift: 25C vs 15C for 16 hours at L4 larva stage.	Transcripts that showed significantly decreased expression in AFD neurons at lin-15(n765ts); oyIs95 animals shifted from 20C to 25C for 16 hours at L4 larva stage, comparing to animals shifted from 20C to 15C for 16 hours at L4 larva stage.	DESeq2, fold change > 2, FDR < 0.05.	WBPaper00065158:25C_vs_15C_downregulated_AFD
	Transcripts that showed significantly decreased expression in cua-1(knu790) comparing to in N2.	FDR < 0.05 and fold change > 2.	WBPaper00066160:cua-1(knu790)_downregulated
	Transcripts interacting with LAG-1 at L4 larva stage in germline ChIP-Seq analysis.	edgeR fold change >= 2, FDR <= 0.05.	WBPaper00059440:LAG-1_interacting_germline
	Transcripts that showed significantly increased expression in meg-1(vr10) meg-2(RNAi) comparing to in N2 animals.	DESeq2, fold change > 2, FDR < 0.05.	WBPaper00064559:meg-1(vr10)meg-2(RNAi)_upregulated
	Transcripts that showed significantly decreased expression in rrf-3(pk1426) comparing to in N2 at embryo stage.	DESeq2v 1.18.1, fold change > 1.5, adjusted p-value < 0.01.	WBPaper00056169:rrf-3(pk1426)_downregulated_embryo
	Transcripts the interact with GFP-CAR-1 according to single-end enhanced crosslinking and immunoprecipitation (seCLIP).	Cuffdiff (p value < 0.05)	WBPaper00059203:CAR-1_interacting
	Transcripts repressed by lag-1(oz536oz537), in the gld-2(q497)gld-1(q485); glp-1(ar202) background at young adult stage after 48 hours of 1mM auxin treatment.	edgeR fold change >= 2, FDR <= 0.05.	WBPaper00059440:LAG-1_repressed_48hr-auxin
	Genes that exhibit a differential enrichment (p-value < 0.05 and a fold enrichment (log2fold)> 0.5) between the ADR-2 IPs from adr-1(tm668) worms and adr-2(ok735) worm.	DESeq2, p-value < 0.05 and a fold enrichment log2fold > 0.5.	WBPaper00055226:ADR-2_target_adr-1(tm668)
	Transcripts that showed significantly increased expression in ptrn-1(tm5597) comparing to in N2	DESeq2 1.14.1, fold change > 1.5, p-value < 0.01.	WBPaper00056039:ptrn-1(tm5597)_upregulated

0 Expression Patterns

0 GO Annotation

0 Homologues

1 Locations

• Feature . Primary Identifier: WBGene00219949
• Start: 11756785
• End: 11756919
• Strand: 1

0 Ontology Annotations

0 Regulates Expr Cluster

1 Sequence

• Length: 135

1 Sequence Ontology Term