WormMine: Gene WBGene00006315

• WormBase Gene ID: WBGene00006315
• Gene Name: sup-6
• Sequence Name: F58G1.10
• Brief Description: sup-6 encodes a U1 snRNA required for development to adulthood;sup-6(st19) mutants arrest as late larvae; the sup-6(st19) mutation is adominant, allele-specific suppressor of unc-13(e309), an intronic+1G-to-A transition in unc-13; sup-6(st19) is otherwise recessive, withno obvious phenotype in heterozygotes.
• Organism: Caenorhabditis elegans
• Automated Description: Is affected by several genes including ptl-1; ptrn-1; and etr-1 based on tiling array and RNA-seq studies. Is affected by Tunicamycin and sodium arsenite based on RNA-seq studies.
• Biotype: SO:0001268
• Genetic Position: II :12.5245 ±0.096794
• Length (nt): 165

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Synonyms

• Value: WBGene00006315

Genomics

1 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:F58G1.10	F58G1.10	165	II: 12944803-12944967

Other

0 CDSs

4 RNAi Result

• WBRNAi00022286
• WBRNAi00076128
• WBRNAi00033126
• WBRNAi00063634

6 Allele

• gk963801
• gk963053
• gk962684
• gk962526
• gk962527
• st19

1 Chromosome

• WormBase ID: II
• Organism: Caenorhabditis elegans
• Length (nt): 15279421

1 Chromosome Location

• Feature . Primary Identifier: WBGene00006315
• Start: 12944803
• End: 12944967
• Strand: -1

2 Data Sets

• WormBaseAcedbConverter
• C. elegans genomic annotations (GFF3 Gene)

0 Downstream Intergenic Region

24 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Transcripts that showed significantly increased expression in ogt-1(ok1474) neuronal cells isolated by FACs comparing to in FACs isolated neuronal cells from wild type.	DESeq2, fold change > 2, FDR < 0.05.	WBPaper00066485:ogt-1(ok1474)_upregulated_neuron
Osmotic stress	Transcripts that showed significantly altered expression with 500 mM salt (NaCl) vs 100 mM salt when food was present	DESeq(version 1.10.1), FDR < 0.05.	WBPaper00050726:OsmoticStress_regulated_Food
	Transcripts depleted in purified oocyte P bodies comparing to in whole oocytes.	DESeq2, FDR < 0.05, fold change > 2.	WBPaper00065975:P-body_vs_oocyte_depleted
	Transcripts depleted in purified oocyte P bodies comparing to in the whole animal.	DESeq2, FDR < 0.05, fold change > 2.	WBPaper00065975:P-body_vs_WholeAnimal_depleted
	Transcripts that showed significantly decreased expression in hpl-2(tm1489) comparing to in N2 animals.	DESeq2, adjusted p-value < 0.05, log2 fold change > 2 or < -2.	WBPaper00054493:hpl-2(tm1489)_downregulated
	Transcripts that showed significantly increased expression in dpy-21(e428) comparing to in N2 during L3 stage.	DESeq v1.6.3. Fold change > 1.5.	WBPaper00050370:dpy-21(e428)_L3_upregulated
	Transcripts that showed significantly altered expression in rnp-6(dh1127) animals comparing to in N2 when fed with live S. aureus.	Differentially expressed genes (DEGs) (q-value <0.05) between different samples were identified using the stringtie version 1.3.0, followed by Cufflinks version 2.2.	WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
	Transcripts that showed significantly increased expression in ilc-17.1(syb5296) comparing to in N2 animals at L4 larva stage.	DESeq2, fold change > 2, FDR < 0.05.	WBPaper00066594:ilc-17.1(syb5296)_upregulated
	Transcripts that showed significantly increased expression in animals lacking P granules by RNAi experiments targeting pgl-1, pgl-3, glh-1 and glh-4, and unc-119-GFP(+), comparing to in control animals, at 2-day post L4 adult hermaphrodite stage.	DESeq2, Benjamini-Hochberg multiple hypothesis corrected p-value < 0.05 and fold change > 2.	WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
	Transcripts that showed significantly increased expression in set-2(tm1630) animals at embryo stage, comparing to in N2 animals.	DESeq2 (v2.1.8.3) was used to determine DE genes and to generate principal component and scatter plots. DE genes with FDR < 0.05 were analysed using g:Profiler with Bonferroni correction.	WBPaper00060014:set-2(tm1630)_upregulated
	Transcripts that showed significantly increased expression in sftb-1(cer6) deletion homozygous comparing to to in N2 animals at L4 larva stage.	DESeq2, fold change > 2	WBPaper00058725:sftb-1(cer6)_upregulated
	Transcripts that interact with 3xFLAG-DLC-1 as identified by immunoprecipitation followed by RNA sequencing.	DESeq2, fold change > 2,, p-value < 0.01	WBPaper00055334:DLC-1_interacting
Bacteria infection: Pseudomonas aeruginosa PA14. 24 hours of exposure.	Small RNAs (21-26nt) that showed significantly increased expression after L4 animals were exposed to P .aeruginosa strain PA14 for 24 hours.	DESeq2, FDR < 0.05	WBPaper00056868:P.aeruginosa_upregulated_smallRNA
	Transcripts that showed significantly increased expression in csr-1(RNAi) comparing to in N2 animals fed wth empty vector.	DESeq2 v1.20.0,, fold change > 2, FDR < 0.05.	WBPaper00066919:csr-1(RNAi)_upregulated
	Potental DAF-12 target genes identified by ChIP-chip analysis performed on strain ALF4 [daf-12	Affymetrix TAS software that computed for each probe estimates of fold enrichment (in linear scale) over hybridization with input DNA. At the same time, TAS calculated for each probe a p-value by applying a Wilcoxon signed rank test. A threshold of 2.5 was selected, which corresponds to probe intensities approximately 2.5 times stronger on the ChIP array than on the Input array. Additional TAS threshold parameters were MinRun=180 bp, MaxGap=300 bp. TAS analysis showed that the selected threshold of 2.5 corresponds approximately to a p-value of 0.01.	WBPaper00040221:DAF-12_target_ALF4
	Transcripts that showed significantly increased expression in ptl-1(ok621) comparing to in N2	DESeq2 1.14.1, fold change > 1.5, p-value < 0.01.	WBPaper00056039:ptl-1(ok621)_upregulated
	Transcripts of noncoding genes that showed significantly increased expression in muscle.	DESeq2 (version 1.24.0). Transcripts with a false-discovery rate adjusted p-value less than 0.05 were considered significantly differentially expressed.	WBPaper00062325:muscle_enriched_noncoding-RNA
	Transcripts that showed significantly increased expression in strain CER276 sftb1(cer39[Q552P, R643C,K718E]) comparing to in N2 animals at L4 larva stage.	DESeq2, fold change > 2	WBPaper00058725:sftb-1(cer39)_upregulated
Starvation	Transcripts that showed significantly altered expression by starvation with 500 mM salt (NaCl)	DESeq(version 1.10.1), FDR < 0.05.	WBPaper00050726:starvation_regulated_HighSalt
	Promoters regions that bind with NHR-86 according to ChIP-Seq using NHR-86-GFP protein.	N.A.	WBPaper00056073:NHR-86_interacting_promoter
	Transcripts that showed significantly decreased expression in rrf-3(pk1426) comparing to in N2 at embryo stage.	DESeq2v 1.18.1, fold change > 1.5, adjusted p-value < 0.01.	WBPaper00056169:rrf-3(pk1426)_downregulated_embryo
	Transcripts that showed significantly increased expression after 4 hours of treatment by 50 ub per ml tunicamycin at L4 larva stage, in RtcB(null) animals.	Fold change > 1.75	WBPaper00045971:tunicamycin_upregulated_RtcB(null)
	Genes that showed significantly changed expression in oxidative stressed trx-1(ok1449) animals caused by 10mM sodium arsenite (NaAsO2) comparing to in unstressed trx-1(ok1449).	R-Bioconductor package.	WBPaper00049266:NaAsO2-Stress_regulated_trx-1(ok1449)
	Transcripts that showed significantly increased expression in ptrn-1(tm5597) comparing to in N2	DESeq2 1.14.1, fold change > 1.5, p-value < 0.01.	WBPaper00056039:ptrn-1(tm5597)_upregulated

0 Expression Patterns

0 GO Annotation

0 Homologues

1 Locations

• Feature . Primary Identifier: WBGene00006315
• Start: 12944803
• End: 12944967
• Strand: -1

0 Ontology Annotations

0 Regulates Expr Cluster

1 Sequence

• Length: 165

1 Sequence Ontology Term