WormMine: Gene WBGene00271703

• WormBase Gene ID: WBGene00271703
• Gene Name: ZK1010.12
• Sequence Name: ZK1010.12
• Organism: Caenorhabditis elegans
• Automated Description: Is affected by several genes including hpl-1; hpl-2; and his-24 based on RNA-seq and microarray studies. Is affected by resveratrol and dibromoacetic acid based on microarray studies.
• Biotype: SO:0001217
• Genetic Position: :±
• Length (nt): 1196

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Synonyms

• Value: WBGene00271703

Genomics

1 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:ZK1010.12.1	ZK1010.12.1	393	III: 12991297-12992492

Other

1 CDSs

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:ZK1010.12	ZK1010.12	393	III: 12991297-12991391

2 RNAi Result

• WBRNAi00059039
• WBRNAi00006722

16 Allele

• gk963887
• gk963904
• gk963552
• gk189572
• gk963763
• gk963762
• gk449290
• gk441377
• gk690866
• gk638249
• gk315698
• gk441376
• gk495939
• gk805267
• gk448107
• gk806529

1 Chromosome

• WormBase ID: III
• Organism: Caenorhabditis elegans
• Length (nt): 13783801

1 Chromosome Location

• Feature . Primary Identifier: WBGene00271703
• Start: 12991297
• End: 12992492
• Strand: 1

2 Data Sets

• WormBaseAcedbConverter
• C. elegans genomic annotations (GFF3 Gene)

0 Downstream Intergenic Region

11 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Transcripts that showed significantly increased expression in ogt-1(ok1474) neuronal cells isolated by FACs comparing to in FACs isolated neuronal cells from wild type.	DESeq2, fold change > 2, FDR < 0.05.	WBPaper00066485:ogt-1(ok1474)_upregulated_neuron
	Transcripts that showed significantly increased expression in ubc-9(ne4833[ubc-9(G56R)] in gonads dissected from 1-day old adult animals.	Salmon was used to map the mRNA-seq reads with the worm database WS268, and its output files were imported to DESeq2 in R. The differentially expressed genes were filtered by fold change more than 2 and adjusted p-value < 0.05. The scatter plots were generated by the plot function in R.	WBPaper00061479:ubc-9(ne4833)_upregulated
Heat shock: 34C 30min.	Transcripts that showed significantly increased expression in L2 larva stage C. elegans animals after incubated in a 34C water bath for 30min.	DESeq2 v 1.18.1, fold change > 2, FDR < 0.01.	WBPaper00058955:heatshock_upregulated_CE
	Genes expressed in N2.	Expressed transcripts were identified on the basis of a Present call in 3 out of 4 N2 experiments as determined by Affymetrix MAS 5.0.	WBPaper00025141:N2_Expressed_Genes
	Transcripts that showed significantly increased expression in lin-29(n333) comparing to in N2 at day 1 adult stage.	DESeq2, FDR < 0.01, fold change > 2.	WBPaper00066970:lin-29(n333)_upregulated
	Genes found to be regulated in daf-16(mgDf50) by resveratrol treatment with p < 0.01.	N.A.	WBPaper00026929:Resveratrol_regulated_daf-16
Bacteria infection: Enterococcus faecalis	Genes down-regulated in animals infected with Enterococcus faecalis compared to the E. coli OP50 control after 24h of infection.	MAANOVA and BRB-Array-Tools.	WBPaper00030985:Enterococcus_faecalis_downregulated
	Transcripts that showed significantly decreased expression in postdauer adults comparing to adult animals that bypassed the dauger stage.	DESeq 2, FDR < 0.05.	WBPaper00064494:postdauer_downregulated_WholeAnimal
	Genes that showed decreased expression after 50uM DBAA treatment comparing with control.	Differentially expressed genes (DEGs) were identified with a random variance t test and a significance analysis of microarrays (SAM) test. Genes were considered statistically significant if their p value was less than 0.05, the false discovery rate less than 0.3 and the fold change compared to control at least <= 0.67 or >= 1.5.	WBPaper00045294:50uM_DBAA_downregulated
	Genes with increased expression level for L4 stage larvae in hpl-2; hpl-1 and his-24 hpl-1; hpl-2 compared to wild type (FDR < 0.05).	The gene expression fold change was calculated from the duplicate microarray data. The fold change cut-off was 1.5 from 2 biological replicates (FDR < 0.05). Fold change shown here are hpl-1; hpl-2; his-24 vs WT.	WBPaper00041609:hpl-1_hpl-2_upregulated
	Genome-wide analysis of developmental and sex-regulated gene expression profile.	self-organizing map	cgc4489_group_23

2 Expression Patterns

• Primary Identifier: Expr2026903
• Pattern: Single cell embryonic expression. Only cell types with an expression fraction of greater 0.2 of the maximum expressed fraction are labeled (Full data can be downloaded from http://caltech.wormbase.org/pub/wormbase/datasets-published/packer2019/). The colors represent the broad cell class to which the cell type has been assigned. The size of the point is proportional to the log2 of the numbers of cells in the dataset of that cell type. Interactive visualizations are available as a web app (https://cello.shinyapps.io/celegans/) and can also be installed as an R package (https://github.com/qinzhu/VisCello.celegans).

• Primary Identifier: Expr2008668
• Pattern: Single cell embryonic expression. Only cell types with an expression fraction of greater 0.2 of the maximum expressed fraction are labeled (Full data can be downloaded from http://caltech.wormbase.org/pub/wormbase/datasets-published/packer2019/). The colors represent the broad cell class to which the cell type has been assigned. The size of the point is proportional to the log2 of the numbers of cells in the dataset of that cell type. Interactive visualizations are available as a web app (https://cello.shinyapps.io/celegans/) and can also be installed as an R package (https://github.com/qinzhu/VisCello.celegans).

0 GO Annotation

0 Homologues

1 Locations

• Feature . Primary Identifier: WBGene00271703
• Start: 12991297
• End: 12992492
• Strand: 1

0 Ontology Annotations

0 Regulates Expr Cluster

1 Sequence

• Length: 1196

1 Sequence Ontology Term