WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Gene :

WormBase Gene ID  ? WBGene00195049 Gene Name  CC8.3
Sequence Name  ? CC8.3 Organism  Caenorhabditis elegans
Automated Description  Enriched in ciliated neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including dpy-21; ilc-17.1; and ogt-1 based on RNA-seq studies. Is affected by Ag nanoparticles based on RNA-seq studies. Biotype  SO:0001217
Genetic Position  Length (nt)  ? 894
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Synonyms

Value
WBGene00195049

Genomics

1 Transcripts

WormMine ID Sequence Name Length (nt) Chromosome Location
Transcript:CC8.3.1 CC8.3.1 242   IV: 3641396-3642289
 

Other

1 CDSs

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:CC8.3 CC8.3 234   IV: 3641396-3641543

0 RNAi Result

30 Allele

Public Name
gk963722
WBVar00187650
ttTi24916
WBVar01515140
WBVar01515141
WBVar01515138
WBVar01515139
WBVar01922969
WBVar02082328
WBVar01922966
WBVar01922967
WBVar01922968
WBVar01515136
WBVar01515137
WBVar01515134
WBVar01515135
WBVar02097928
WBVar01515133
WBVar01965954
WBVar01965953
WBVar02109055
WBVar02109054
WBVar01965952
WBVar01838990
WBVar01965951
WBVar00571505
WBVar02036854
gk589973
WBVar02003751
ttTi24894

1 Chromosome

WormBase ID Organism Length (nt)
IV Caenorhabditis elegans 17493829  

1 Chromosome Location


Feature . Primary Identifier
Start End Strand
WBGene00195049 3641396 3642289 -1

2 Data Sets

Name URL
WormBaseAcedbConverter  
C. elegans genomic annotations (GFF3 Gene)  

1 Downstream Intergenic Region

WormBase ID Name Sequence Name Length (nt) Chromosome Location Organism
intergenic_region_chrIV_3640467..3641395   929 IV: 3640467-3641395 Caenorhabditis elegans

12 Expression Clusters

Regulated By Treatment Description Algorithm Primary Identifier
  Transcripts that showed significantly increased expression in L1 neural cells comparing to in adult neural cells. DESeq2 (v1.18.1) fold change > 2, P-adj<0.05, using BenjaminiHochberg correction. WBPaper00060811:L1_vs_adult_upregulated_neural
  Transcripts that showed significantly increased expression in ilc-17.1(syb5296) comparing to in N2 animals at L4 larva stage. DESeq2, fold change > 2, FDR < 0.05. WBPaper00066594:ilc-17.1(syb5296)_upregulated
  Transcripts that showed significantly increased expression in dpy-21(e428) comparing to in N2 during L3 stage. DESeq v1.6.3. Fold change > 1.5. WBPaper00050370:dpy-21(e428)_L3_upregulated
  Transcripts that showed significantly decreased expression in set-2(tm1630) animals at embryo stage, comparing to in N2 animals. DESeq2 (v2.1.8.3) was used to determine DE genes and to generate principal component and scatter plots. DE genes with FDR < 0.05 were analysed using g:Profiler with Bonferroni correction. WBPaper00060014:set-2(tm1630)_downregulated
Starvation Transcripts that showed significantly altered expression by starvation with 100 mM salt (NaCl) DESeq(version 1.10.1), FDR < 0.05. WBPaper00050726:starvation_regulated_LowSalt
  Single-cell RNA-Seq cell group 25_0 expressed in neuron. scVI 0.6.0 WBPaper00065841:25_0
  Transcripts enriched in EVN neurons, by comparing expressin in EVN cells and in whole worm lysates. DESeq was used. Genes overexpressed 2 - 11 fold in EVNs were considered differentially expressed. WBPaper00049001:EVN_enriched
  Transcripts that showed significantly decreased expression in ogt-1(ok1474) neuronal cells isolated by FACs comparing to in FACs isolated neuronal cells from wild type. DESeq2, fold change > 2, FDR < 0.05. WBPaper00066485:ogt-1(ok1474)_downregulated_neuron
  Single-cell RNA-Seq cell group 25_1 expressed in neuron. scVI 0.6.0 WBPaper00065841:25_1
  Top 300 transcripts enriched in IL2L, IL2R, IL2DL, IL2DR, IL2VL, IL2VR according to single cell RNAseq. Top 300 enriched transcripts were determined by log2.ratio of the tpm in the cell type vs the tpm in the other cells * the log2 of the cell.type tpm. WBPaper00061340:IL2
  Transcripts enriched in IL2_LR according to single cell RNAseq. Genes that pass the Bonferroni threshold for multiple comparisons (q < 0.05) are significantly enriched. WBPaper00061651:IL2_LR_enriched
  Transcripts that showed significantly decreased expression after exposed to 10ug per ml Ag nanoparticles from L1 larva to 1-day post L4 adult hermaphrodite stage. edgeR, fold change > 2 (set by curator), FDR < 0.05. WBPaper00059426:Ag-nanoparticles_downregulated

3 Expression Patterns

Remark Reporter Gene Primary Identifier Pattern Subcellular Localization
    Expr2020213 Single cell embryonic expression. Only cell types with an expression fraction of greater 0.2 of the maximum expressed fraction are labeled (Full data can be downloaded from http://caltech.wormbase.org/pub/wormbase/datasets-published/packer2019/). The colors represent the broad cell class to which the cell type has been assigned. The size of the point is proportional to the log2 of the numbers of cells in the dataset of that cell type. Interactive visualizations are available as a web app (https://cello.shinyapps.io/celegans/) and can also be installed as an R package (https://github.com/qinzhu/VisCello.celegans).  
    Expr2001989 Single cell embryonic expression. Only cell types with an expression fraction of greater 0.2 of the maximum expressed fraction are labeled (Full data can be downloaded from http://caltech.wormbase.org/pub/wormbase/datasets-published/packer2019/). The colors represent the broad cell class to which the cell type has been assigned. The size of the point is proportional to the log2 of the numbers of cells in the dataset of that cell type. Interactive visualizations are available as a web app (https://cello.shinyapps.io/celegans/) and can also be installed as an R package (https://github.com/qinzhu/VisCello.celegans).  
    Expr1147279 Developmental gene expression time-course. Raw data can be downloaded from ftp://caltech.wormbase.org/pub/wormbase/datasets-published/hashimshony2015  

0 GO Annotation

0 Homologues

1 Locations


Feature . Primary Identifier
Start End Strand
WBGene00195049 3641396 3642289 -1

0 Ontology Annotations

0 Regulates Expr Cluster

1 Sequence

Length
894

1 Sequence Ontology Term