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Transcripts that showed significantly increased expression glp-1(e2141); TU3401 animals comparing to in TU3401 animals. |
Fold change > 2, FDR < 0.01. |
WBPaper00065993:glp-1(e2141)_upregulated
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Transcripts that showed significantly decreased expression in unc-70(cas983) comparing to in N2 at L1 larva stage. |
DESeq2, fold change >= 2, FDR <= 0.05 |
WBPaper00057041:unc-70(cas983)_downregulated
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Transcripts that showed significantly increased expression in sensory neuron (labeled by iaIs25[Pgcy-37::GFP + unc-119(+)]) comparing to in whole worm. |
Fold change > 2, p-value < 0.05. |
WBPaper00060661:sensory-neuron_enriched
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Genes that showed significantly decreased expression in hrp-2(RNAi) animals comparing to in control animals. |
DESeq2, adjusted p-value < 0.1, log2 Fold change >= 2 or <= -2. |
WBPaper00050504:hrp-2(RNAi)_downregulated
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Micro RNAs that showed significantly decreased expression in day 8 adults comparing to in day 1 adults in intestine. |
Differentially expressed miRNAs were identified using DEGseq based on unique molecular identifier (UMI). A minimum UMI sum of 10 in 3 replicates was set as the threshold of expression. MiRNAs with more than five reads were defined as expressed. Differential expression of miRNAs was analysed by t-test (P value < 0.05 and fold-change > 1.5 or < 0.67) after Box-Cox transformation. MiRNA targets were identified by TargetScanWorm (Release 6.2) and Pearson Correlation Coefficient smaller than -0.2. |
WBPaper00066447:Day8_vs_Day1_downregulated_intestine
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miRNA that showed increased expression after 20mM nicotine treatment |
Statistical analysis was based on t-test for independent samples via SPSS. The results were further narrowed based on two criteria. Only the genes whose expression changed with a P < 0.05 and a fold change > 0.5, when compared to control, were considered as differentially expressed. Fold change was calculated as 2**(DeltaCt(treatment)-DeltaCt(control))-1. DeltaCt = Ct(miRNA)-Ct(aveMRNA). |
WBPaper00042480:20mM_nicotine_upregulated
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Fasting for 48 hours, from 3 days post L4 to 5 days post L4. |
MicroRNAs that showed significantly decreased expression after 48 hours of fasting |
p < 0.0002, Fishers exact test. |
WBPaper00051247:fasting_downregulated
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Micro RNAs that showed significantly decreased expression in hrpk-1(zen17) comparing to in N2 at embryo stage. |
DESeq, fold change > 2, p-value <= 0.05. |
WBPaper00058673:hrpk-1(zen17)_downregulated_miRNA_embryo
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Bacteria infection: Pseudomonas aeruginosa PA14 |
miRNAs up regulated by Pseudomonas aeruginosa infection. |
N.A. |
WBPaper00046303:P.aeruginosa_upregulated_miRNA
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Micro RNAs that showed significantly lower expression (log2fold > 2, padj < 0.01) in hermaphrodite gonad (somatic gonad plus germine) than in male gonad (somatic gonad plus germine). |
DESeq2 v1.13.8, fold change > 2, FDR < 0.01. |
WBPaper00056161:male_enriched_miRNA
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Micro RNAs that showed significantly increased expression in animals after 24 hour exposure to 100ug per ml silica nanoparticles (SiNPs). |
The random variance model (RVM)t-test was applied toidentify differentially expressed mRNAs and miRNAsbetween the SiNPs-treated group and the control group. P-value <0.05 and fold change (FC) >1.5 were considered as the threshold screening between the SiNP-treated groupand the control group. |
WBPaper00060100:SiNP_upregulated_miRNA
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