WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Gene :

WormBase Gene ID  ? WBGene00017191 Gene Name  F07B7.13
Sequence Name  ? F07B7.13 Organism  Caenorhabditis elegans
Automated Description  Enriched in body wall musculature; pharynx; somatic nervous system; tail neurons; and vulval muscle based on Chronogram studies. Is affected by several genes including etr-1; ash-2; and pfd-6 based on RNA-seq studies. Is affected by four chemicals including allantoin; Sirolimus; and rifampin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). Biotype  SO:0001217
Genetic Position  Length (nt)  ? 693
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Synonyms

Value
WBGene00017191

Genomics

1 Transcripts

WormMine ID Sequence Name Length (nt) Chromosome Location
Transcript:F07B7.13.1 F07B7.13.1 609   V: 8863960-8864652
 

Other

1 CDSs

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:F07B7.13 F07B7.13 609   V: 8863960-8864013

5 RNAi Result

WormBase ID
WBRNAi00039285
WBRNAi00039286
WBRNAi00039287
WBRNAi00009906
WBRNAi00028273

6 Allele

Public Name
gk963301
gk964351
gk962860
gk964052
gk963442
gk963441

1 Chromosome

WormBase ID Organism Length (nt)
V Caenorhabditis elegans 20924180  

1 Chromosome Location


Feature . Primary Identifier
Start End Strand
WBGene00017191 8863960 8864652 -1

2 Data Sets

Name URL
WormBaseAcedbConverter  
C. elegans genomic annotations (GFF3 Gene)  

1 Downstream Intergenic Region

WormBase ID Name Sequence Name Length (nt) Chromosome Location Organism
intergenic_region_chrV_8862050..8863959   1910 V: 8862050-8863959 Caenorhabditis elegans

25 Expression Clusters

Regulated By Treatment Description Algorithm Primary Identifier
  mRNAs that showed decreased expression in 1 cell mebryo comparing to in oocyte, according to RNAseq analysis. Gaussian error propagation. As cutoff for the up-regulated genes authors used log2 fold change > 1 and P < 0.05 and as cutoff for the down-regulated genes authors used log2 fold change < -1 and P < 0.05. WBPaper00045420:fertilization_downregulated_transcript
Bacteria infection: Enterococcus faecalis Genes with increased expression after 24 hours of infection by E.faecalis Fold changes shown are pathogen vs OP50. For RNA-seq and tiling arrays, log2 fold changes between gene expression values of infected versus uninfected nematodes were calculated. For log2 fold changes > 0.00001 the values > 81.25th percentile were defined as up-regulated and for log2 fold changes < -0.00001 the values < 18.75th percentile were defined as down-regulated. WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
  Genes that are significantly up regulated in tdp-1(ok803) poly(A) RNA-seq verses in N2. DESeq v1.14, with cut-off p-value < 0.05 and FDR < 0.1. WBPaper00046012:tdp-1(ok803)_upregulated
  Transcripts that showed significantly decreased expression in daf-16(mgDf50) comparing to in N2 at L1 larva stage. DESeq v1.20.0 was used to analyze differential gene expression. Transcripts with adjusted p-value < 0.05 were considered differentialled expressed. WBPaper00048971:daf-16(mgDf50)_downregulated_L1
  Transcripts that showed significantly decreased expression in daf-2(e1370); daf-18(nr2037) comparing to in daf-2(e1370) animals. Differentially expressed genes (fold change > 2 and adjusted p value < 0.05) were identified by using DESeq2 (v.1.22.2). WBPaper00061952:daf-18(nr2037)_downregulated
  Transcripts that showed significantly decreased expression in eat-2(ad1116) comparing to in N2 at 3-days post L4 adult hermaphrodite animals. DESeq2(v1.14.1), fold change > 2, p-value < 0.05 WBPaper00055354:eat-2(ad1116)_downregulated
  Transcripts that showed significantly decreased expression after animals were treated with 100uM Rapamycin and 250uM Allantoin from day 1 to day 3 adult hermaphradite. DESeq2(v1.14.1), fold change > 2, p-value < 0.05 WBPaper00055354:Rapamycin-Allantoin_downregulated
  Transcripts that showed significantly increased expression in nas-38(ok3407) comparing to in N2. A feature was classified upregulated if its FDR-corrected p-value was <= 0.05 and fold change was >= 2. Analogously, a gene was classified downregulated if its FDR-corrected p-value was <= 0.05 and fold change was <= -2. WBPaper00060703:nas-38(ok3407)_upregulated
  Transcripts of coding genes that showed significantly increased expression in muscle. DESeq2 (version 1.24.0). Transcripts with a false-discovery rate adjusted p-value less than 0.05 were considered significantly differentially expressed. WBPaper00062325:muscle_enriched_coding-RNA
Bacteria infection: Photorhabdus luminescens Genes with increased expression after 24 hours of infection by P.lumniescens Fold changes shown are pathogen vs OP50. For RNA-seq and tiling arrays, log2 fold changes between gene expression values of infected versus uninfected nematodes were calculated. For log2 fold changes > 0.00001 the values > 81.25th percentile were defined as up-regulated and for log2 fold changes < -0.00001 the values < 18.75th percentile were defined as down-regulated. WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
  Transcripts that showed significantly decreased expression after animals were treated with 50uM Rifampicin and 100uM Psora from day 1 to day 3 adult hermaphradite. DESeq2(v1.14.1), fold change > 2, p-value < 0.05 WBPaper00055354:Rifampicin-Psora_downregulated
  Transcripts that showed significantly decreased expression in ash-2(RNAi) comparing to in wild type animals injected with vector. Differential mRNA expression using DESeq2. mRNAs with a FDR < 0.05 and fold change > 2 considered differentially expressed. WBPaper00066232:ash-2(RNAi)_downregulated_WT
  Enriched in ventral nerve cord (adult).   WBPaper00029359_1166
  Enriched in vulval muscle (adult), ventral nerve cord (larva), ventral nerve cord (adult), dorsal nerve cord (adult), body neurons (adult), body neurons (larva), tail neurons (larva), nerve ring (larva), dorsal nerve cord (larva), nerve ring (adult), body wall muscle (larva), lateral nerve cords/commissures (larva).   WBPaper00029359_1197
  Enriched in ventral nerve cord (larva), vulval muscle (adult), ventral nerve cord (adult), body neurons (adult), body neurons (larva), dorsal nerve cord (adult), tail neurons (larva), dorsal nerve cord (larva), nerve ring (adult), nerve ring (larva), tail neurons (adult), body wall muscle (larva).   WBPaper00029359_1291
  Transcripts that showed significantly increased expression in daf-2(e1370) comparing to in N2. Limma version 3.24.15. Fold change < 0.67 (p < 0.05). WBPaper00055827:daf-2(e1370)_upregulated
  Enriched in pharynx).   WBPaper00029359_1458
  Enriched in vulval muscle (adult), ventral nerve cord (larva), ventral nerve cord (adult), dorsal nerve cord (adult), body neurons (adult), body neurons (larva), tail neurons (larva), nerve ring (larva), nerve ring (adult), dorsal nerve cord (larva), body wall muscle (larva), lateral nerve cords/commissures (larva), tail neurons (adult).   WBPaper00029359_1546
  Co-expression group from Chronogram study.   WBPaper00029359_1549
  Co-expression group from Chronogram study.   WBPaper00029359_1557
  Co-expression group from Chronogram study.   WBPaper00029359_1599
  Transcripts that showed significantly increased expression in pfd-6(gk493446); daf-2(e1370) comparing to in daf-2(e1370). Limma version 3.24.15. Fold change < 0.67 (p < 0.05). WBPaper00055827:pfd-6(gk493446)_upregulated
  Enriched in pharynx), pharynx).   WBPaper00029359_1345
  Enriched in pharynx).   WBPaper00029359_1326
  Enriched in pharynx).   WBPaper00029359_1439

2 Expression Patterns

Remark Reporter Gene Primary Identifier Pattern Subcellular Localization
Original chronogram file: chronogram.134.xml [F07B7.13:gfp] transcriptional fusion. Chronogram319    
    Expr1147840 Developmental gene expression time-course. Raw data can be downloaded from ftp://caltech.wormbase.org/pub/wormbase/datasets-published/hashimshony2015  

0 GO Annotation

0 Homologues

1 Locations


Feature . Primary Identifier
Start End Strand
WBGene00017191 8863960 8864652 -1

0 Ontology Annotations

0 Regulates Expr Cluster

1 Sequence

Length
693

1 Sequence Ontology Term