WormMine: Gene WBGene00201646

• WormBase Gene ID: WBGene00201646
• Gene Name: ZC412.13
• Sequence Name: ZC412.13
• Organism: Caenorhabditis elegans
• Automated Description: Enriched in neurons based on RNA-seq studies. Is affected by several genes including fzo-1; mrps-5; and hpl-2 based on RNA-seq and microarray studies. Is affected by five chemicals including multi-walled carbon nanotube; iron oxide nanoparticle; and silicon dioxide nanoparticle based on RNA-seq and microarray studies.
• Biotype: SO:0001263
• Genetic Position: :±
• Length (nt): 133

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Synonyms

• Value: WBGene00201646

Genomics

1 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:ZC412.13	ZC412.13	133	V: 14851339-14851471

Other

0 CDSs

0 RNAi Result

9 Allele

• gk963271
• gk963301
• gk964458
• gk964459
• gk963796
• gk963805
• gk254595
• gk381580
• WBVar00017365

1 Chromosome

• WormBase ID: V
• Organism: Caenorhabditis elegans
• Length (nt): 20924180

1 Chromosome Location

• Feature . Primary Identifier: WBGene00201646
• Start: 14851339
• End: 14851471
• Strand: -1

2 Data Sets

• WormBaseAcedbConverter
• C. elegans genomic annotations (GFF3 Gene)

1 Downstream Intergenic Region

• WormBase ID: intergenic_region_chrV_14851239..14851338
• Length (nt): 100
• Chromosome Location: V: 14851239-14851338
• Organism: Caenorhabditis elegans

18 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Neuronally enriched transcripts according to a comparison of neuronal nuclei IP samples to total nuclei using isolation of nuclei from tagged specific cell types (INTACT) technology.	DESEQ2, fold change > 2 and FDR < 0.01.	WBPaper00062103:neuron_enriched
	Transcripts that showed significantly decreased expression in N2 animals exposed to 0.1mM Paraquat from hatching to reaching adult stage.	DESeq2 version 1.22.2, p < 0.05	WBPaper00064716:paraquat_downregulated
	Transcripts that showed signifcantly increased expression in pabp-2(RNAi) animals comparing to in N2 animals injected with empty vector at L1 larva stage and collected at L4 larva stage.	FDR < 0.05, fold change > 2	WBPaper00067368:pabp-2(RNAi)_upregulated_N2
	Transcripts that showed significantly decreased exression in animals exposed to 100uM cadmium for 24 hours.	DESeq2 v1.20.0, fold change > 2, FDR < 0.05.	WBPaper00065029:cadmium_downregulated
	Transcripts that showed significantly decreased expression in hpl-2(tm1489) comparing to in N2 animals.	DESeq2, adjusted p-value < 0.05, log2 fold change > 2 or < -2.	WBPaper00054493:hpl-2(tm1489)_downregulated
	Transcripts that showed significantly increased expression in ilc-17.1(syb5296) comparing to in N2 animals at L4 larva stage.	DESeq2, fold change > 2, FDR < 0.05.	WBPaper00066594:ilc-17.1(syb5296)_upregulated
	Transcripts that showed significantly increased expression in pmt-2(RNAi) animals comparing to control animals iinjected with empty vector.	Fold-change > 1.5, ANOVA P values < 0.05.	WBPaper00055482:pmt-2(RNAi)_upregulated
	Transcripts that showed significantly increased expression in animals after 24 hour exposure to 100ug per ml silica nanoparticles (SiNPs).	The random variance model (RVM)t-test was applied toidentify differentially expressed mRNAs and miRNAsbetween the SiNPs-treated group and the control group. P-value <0.05 and fold change (FC) >1.5 were considered as the threshold screening between the SiNP-treated groupand the control group.	WBPaper00060100:SiNP_upregulated_mRNA
	Genes that showed significantly decreased expression after exposure to 1mg/L MWCNTs from L1 larva to young adult.	Transcripts with false discovery rate-corrected p-values < 0.05 and fold change > 2 were defined as differentially expressed.	WBPaper00049377:MWCNT_downregulated
	Transcripts that showed significantly increased expression in zcIs13; twnEx320[Punc-119-ds-fzo-1] comparing to in zcIs13[Phsp-6-gfp] animals.	Fold change >= 1.5.	WBPaper00061409:neuronal-fzo-1(RNAi)_upregulated
	Transcripts that showed significantly increased expression in lpd-3(ok2138) comparing to in N2 animals.	DESeq2, fold change > 4, FDR < 0.05.	WBPaper00064661:lpd-3(ok2138)_upregulated
	Transcripts that showed signifcantly increased expression in ubr-5(miy31);pabp-2(RNAi) animals comparing to in ubr-5(miy31) animals injected with empty vector at L1 larva stage and collected at L4 larva stage.	FDR < 0.05, fold change > 2	WBPaper00067368:pabp-2(RNAi)_upregulated_ubr-5(miy31)
	Transcripts that showed signifcantly decreased expression in ubr-5(miy31) injected with empty vector comparing to in N2 animals injected with empty vector at L1 larva stage and collected at L4 larva stage.	FDR < 0.05, fold change > 2	WBPaper00067368:ubr-5(miy31)_downregulated_N2
	Transcripts that showed significantly decreased expression in daf-2(e1370) comparing to in N2.	Student's t-test, fold change > 2, p-value < 0.05.	WBPaper00055386:daf-2(e1370)_downregulated
	Transcripts that showed significantly decreased expression in mrps-5(RNAi) animals comparing to animals injected with empty vector.	Differential expression was assessed using a Partial least-squares discriminant analysis (PLS-DA) using mixomics setting a variable of importance (VIP) score of greater than 1 as significant.	WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
	Transcripts that showed signifcantly decreased expression in ubr-5(miy31);pabp-2(RNAi) comparing to in pabp-2(RNAi) animals.	FDR < 0.05, fold change > 2	WBPaper00067368:ubr-5(miy31)_downregulated_pabp-2(RNAi)
	Transcripts that showed significantly increased expression in ifo-1(kc2) comparing to in N2 animals.	ANOVA, p-value < 0.05.	WBPaper00056167:ifo-1(kc2)_upregulated
	Most down-regulated genes after Cit-SPIONs exposure (p<0.01).	Past 3.03 was used for all statistical analyses. Statistical significance between two groups was assessed by t tests. A gene is determined to be differentially expressed when p < 0.01 and only 75 genes were selected as differentially regulated for each expression cluster.	WBPaper00051437:Cit-SPIONs_downregulated

0 Expression Patterns

0 GO Annotation

0 Homologues

1 Locations

• Feature . Primary Identifier: WBGene00201646
• Start: 14851339
• End: 14851471
• Strand: -1

0 Ontology Annotations

0 Regulates Expr Cluster

1 Sequence

• Length: 133

1 Sequence Ontology Term