WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0033176 proton-transporting V-type ATPase complex GO

Namespace  cellular_component Obsolete  false
Description  A proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. The resulting transmembrane electrochemical potential of H+ is used to drive a variety of (i) secondary active transport systems via H+-dependent symporters and antiporters and (ii) channel-mediated transport systems. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis. V-type ATPases are found in the membranes of organelles such as vacuoles, endosomes, and lysosomes, and in the plasma membrane.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

3 Ontology Annotations

Annotation Extension Qualifier
  part_of
  part_of
  part_of

13 Parents

Identifier Name Description
GO:1902494 catalytic complex A protein complex which is capable of catalytic activity.
GO:0032991 protein-containing complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
GO:0005575 cellular_component A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).
GO:0110165 cellular anatomical structure A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses.
GO:0098796 membrane protein complex Any protein complex that is part of a membrane.
GO:0016020 membrane A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.
GO:1990351 transporter complex A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells.
GO:1902495 transmembrane transporter complex A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other.
GO:0016469 proton-transporting two-sector ATPase complex A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible.
GO:0090533 cation-transporting ATPase complex Protein complex that carries out the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in).
GO:0033176 proton-transporting V-type ATPase complex A proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. The resulting transmembrane electrochemical potential of H+ is used to drive a variety of (i) secondary active transport systems via H+-dependent symporters and antiporters and (ii) channel-mediated transport systems. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis. V-type ATPases are found in the membranes of organelles such as vacuoles, endosomes, and lysosomes, and in the plasma membrane.
GO:0098533 ATPase dependent transmembrane transport complex A transmembrane protein complex that functions in ATPase dependent active transport across a membrane.
GO:1904949 ATPase complex A protein complex which is capable of ATPase activity.

27 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0033176 GO:0000220
part of GO:0033176 GO:0000221
part of GO:0033176 GO:0000222
part of GO:0033176 GO:0000223
is_a GO:0033176 GO:0016471
is_a GO:0033176 GO:0016471
is_a GO:1904949 GO:0033176
is_a GO:0090533 GO:0033176
is_a GO:0016469 GO:0033176
is_a GO:0032991 GO:0033176
part of GO:0016020 GO:0033176
is_a GO:0098796 GO:0033176
is_a GO:1902495 GO:0033176
part of GO:0005575 GO:0033176
part of GO:0110165 GO:0033176
is_a GO:1902494 GO:0033176
is_a GO:0098533 GO:0033176
is_a GO:0005575 GO:0033176
is_a GO:1990351 GO:0033176
part of GO:0033176 GO:0033179
part of GO:0033176 GO:0033180
is_a GO:0033176 GO:0033181
is_a GO:0033176 GO:0033181
part of GO:0033176 GO:0046610
is_a GO:0033176 GO:0046611
is_a GO:0033176 GO:0046611
part of GO:0033176 GO:0046612

1 Synonyms

Name Type
hydrogen-translocating V-type ATPase complex synonym