33 Parents
| Identifier | Name | Description |
|---|---|---|
| GO:1902494 | catalytic complex | A protein complex which is capable of catalytic activity. |
| GO:0032991 | protein-containing complex | A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. |
| GO:0005737 | cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| GO:0005575 | cellular_component | A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). |
| GO:0005622 | intracellular anatomical structure | A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm. |
| GO:0110165 | cellular anatomical structure | A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses. |
| GO:0043227 | membrane-bounded organelle | Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. |
| GO:0043226 | organelle | Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane. |
| GO:0043229 | intracellular organelle | Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. |
| GO:0043231 | intracellular membrane-bounded organelle | Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. |
| GO:0098796 | membrane protein complex | Any protein complex that is part of a membrane. |
| GO:0016020 | membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. |
| GO:0098588 | bounding membrane of organelle | The lipid bilayer that forms the outer-most layer of an organelle. |
| GO:0031090 | organelle membrane | A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle. |
| GO:0016471 | vacuolar proton-transporting V-type ATPase complex | A proton-transporting two-sector ATPase complex found in the vacuolar membrane, where it acts as a proton pump to mediate acidification of the vacuolar lumen. |
| GO:0005774 | vacuolar membrane | The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell. |
| GO:0005773 | vacuole | A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. |
| GO:1990351 | transporter complex | A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells. |
| GO:1902495 | transmembrane transporter complex | A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other. |
| GO:0016469 | proton-transporting two-sector ATPase complex | A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible. |
| GO:0090533 | cation-transporting ATPase complex | Protein complex that carries out the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in). |
| GO:0033176 | proton-transporting V-type ATPase complex | A proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. The resulting transmembrane electrochemical potential of H+ is used to drive a variety of (i) secondary active transport systems via H+-dependent symporters and antiporters and (ii) channel-mediated transport systems. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis. V-type ATPases are found in the membranes of organelles such as vacuoles, endosomes, and lysosomes, and in the plasma membrane. |
| GO:0098533 | ATPase dependent transmembrane transport complex | A transmembrane protein complex that functions in ATPase dependent active transport across a membrane. |
| GO:1904949 | ATPase complex | A protein complex which is capable of ATPase activity. |
| GO:0000221 | vacuolar proton-transporting V-type ATPase, V1 domain | The V1 domain of a proton-transporting V-type ATPase found in the vacuolar membrane. |
| GO:0033180 | proton-transporting V-type ATPase, V1 domain | A protein complex that forms part of a proton-transporting V-type ATPase and catalyzes ATP hydrolysis. The V1 complex consists of: (1) a globular headpiece with three alternating copies of subunits A and B that form a ring, (2) a central rotational stalk composed of single copies of subunits D and F, and (3) a peripheral stalk made of subunits C, E, G and H. Subunits A and B mediate the hydrolysis of ATP at three reaction sites associated with subunit A. |
| GO:0033178 | proton-transporting two-sector ATPase complex, catalytic domain | A protein complex that forms part of a proton-transporting two-sector ATPase complex and catalyzes ATP hydrolysis or synthesis. The catalytic domain (F1, V1, or A1) comprises a hexameric catalytic core and a central stalk, and is peripherally associated with the membrane when the two-sector ATPase is assembled. |
| GO:0000323 | lytic vacuole | A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases. |
| GO:0098852 | lytic vacuole membrane | The lipid bilayer surrounding a lytic vacuole and separating its contents from the cytoplasm of the cell. |
| GO:0005764 | lysosome | A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions. |
37 Relations
| Relationship |
Parent Term . Identifier |
Child Term . Identifier |
|---|---|---|
| part of | GO:0005764 | GO:0046612 |
| is_a | GO:0000221 | GO:0046612 |
| part of | GO:0046611 | GO:0046612 |
| is_a | GO:0033180 | GO:0046612 |
| is_a | GO:0098796 | GO:0046612 |
| part of | GO:0033176 | GO:0046612 |
| is_a | GO:0033178 | GO:0046612 |
| part of | GO:0005737 | GO:0046612 |
| part of | GO:0098588 | GO:0046612 |
| part of | GO:1990351 | GO:0046612 |
| part of | GO:0043231 | GO:0046612 |
| part of | GO:0005774 | GO:0046612 |
| part of | GO:0016020 | GO:0046612 |
| part of | GO:0005773 | GO:0046612 |
| part of | GO:0005575 | GO:0046612 |
| part of | GO:0000323 | GO:0046612 |
| part of | GO:1902494 | GO:0046612 |
| part of | GO:0016469 | GO:0046612 |
| part of | GO:1902495 | GO:0046612 |
| part of | GO:0032991 | GO:0046612 |
| part of | GO:0090533 | GO:0046612 |
| is_a | GO:0032991 | GO:0046612 |
| part of | GO:0098796 | GO:0046612 |
| part of | GO:0098852 | GO:0046612 |
| part of | GO:0098533 | GO:0046612 |
| is_a | GO:0033180 | GO:0046612 |
| part of | GO:0016471 | GO:0046612 |
| is_a | GO:0005575 | GO:0046612 |
| part of | GO:0043226 | GO:0046612 |
| part of | GO:1904949 | GO:0046612 |
