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Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0001217 DNA-binding transcription repressor activity GO
Namespace  molecular_function Obsolete  false
Description  A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets.
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0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

5 Ontology Annotations

Annotation Extension Qualifier
  enables
  enables
  enables
  enables
  enables

36 Parents

Identifier Name Description
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0060255 regulation of macromolecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0080090 regulation of primary metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0019219 regulation of nucleobase-containing compound metabolic process Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0003676 nucleic acid binding Binding to a nucleic acid.
GO:0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0048523 negative regulation of cellular process Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0045892 negative regulation of DNA-templated transcription Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
GO:0009890 negative regulation of biosynthetic process Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances.
GO:0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0010468 regulation of gene expression Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).
GO:0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.
GO:0045934 negative regulation of nucleobase-containing compound metabolic process Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:2001141 regulation of RNA biosynthetic process Any process that modulates the frequency, rate or extent of RNA biosynthetic process.
GO:0051252 regulation of RNA metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA.
GO:0051253 negative regulation of RNA metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA.
GO:1902679 negative regulation of RNA biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process.
GO:0010556 regulation of macromolecule biosynthetic process Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0010558 negative regulation of macromolecule biosynthetic process Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0006355 regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
GO:0010605 negative regulation of macromolecule metabolic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:1990837 sequence-specific double-stranded DNA binding Binding to double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding.
GO:0003677 DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0003690 double-stranded DNA binding Binding to double-stranded DNA.

42 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
part of GO:0045892 GO:0001217
has part GO:0000976 GO:0001217
is_a GO:0003700 GO:0001217
is_a GO:0140110 GO:0001217
part of GO:0045892 GO:0001217
part of GO:0019219 GO:0001217
part of GO:0010468 GO:0001217
part of GO:0051253 GO:0001217
part of GO:0080090 GO:0001217
is_a GO:0003674 GO:0001217
part of GO:0051252 GO:0001217
has part GO:1990837 GO:0001217
part of GO:0050789 GO:0001217
is_a GO:0140110 GO:0001217
part of GO:0048519 GO:0001217
part of GO:0010605 GO:0001217
has part GO:0001067 GO:0001217
has part GO:0043565 GO:0001217
part of GO:0006355 GO:0001217
has part GO:0005488 GO:0001217
has part GO:0000976 GO:0001217
part of GO:0008150 GO:0001217
part of GO:0010558 GO:0001217
part of GO:0009889 GO:0001217
part of GO:0010556 GO:0001217
part of GO:2001141 GO:0001217
part of GO:0019222 GO:0001217
part of GO:0050794 GO:0001217
part of GO:0048523 GO:0001217
has part GO:0003690 GO:0001217

16 Synonyms

Name Type
bacterial-type DNA binding transcription repressor activity synonym
bacterial-type RNA polymerase transcriptional repressor activity, cadmium ion regulated sequence-specific DNA binding synonym
bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription synonym
bacterial-type RNA polymerase transcriptional repressor activity, metal ion regulated sequence-specific DNA binding synonym
bacterial-type RNA polymerase transcriptional repressor activity, copper ion regulated sequence-specific DNA binding synonym
cadmium ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription synonym
bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding synonym
metal ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription synonym
copper ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription synonym
transcriptional repressor activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding synonym
sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription synonym
GO:0001141 alt_id
transcriptional repressor activity, bacterial-type RNA polymerase proximal promoter sequence-specific DNA binding synonym
GO:0001219 alt_id
GO:0001218 alt_id
GO:0001220 alt_id