WormMine: GOTerm GO:0045892 negative regulation of DNA-templated transcription GO

• Namespace: biological_process
• Obsolete: false
• Description: Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.

0 Cross References

1 Data Sets

• GO Annotation data set

1 Ontology

• Name: GO

106 Ontology Annotations

38 Parents

Identifier	Name	Description
GO:0009987	cellular process	Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150	biological_process	A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0044238	primary metabolic process	The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0090304	nucleic acid metabolic process	Any cellular metabolic process involving nucleic acids.
GO:0006139	nucleobase-containing compound metabolic process	Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0008152	metabolic process	A cellular process consisting of the biochemical pathways by which a living organism transforms chemical substances. This includes including anabolism (biosynthetic process) and catabolism (catabolic process). Metabolic processes includes the transformation of small molecules, as well macromolecular processes such as DNA repair and replication, protein synthesis and degradation.
GO:0043170	macromolecule metabolic process	The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0065007	biological regulation	Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0019222	regulation of metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0050794	regulation of cellular process	Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0060255	regulation of macromolecule metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0080090	regulation of primary metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0019219	regulation of nucleobase-containing compound metabolic process	Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0050789	regulation of biological process	Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0009058	biosynthetic process	A cellular process consisting of the biochemical pathways by which a living organism synthesizes chemical substances. This typically represents the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
GO:0009059	macromolecule biosynthetic process	The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0048519	negative regulation of biological process	Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0048523	negative regulation of cellular process	Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0045892	negative regulation of DNA-templated transcription	Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
GO:0141187	nucleic acid biosynthetic process	The biosynthetic process resulting in the formation of a nucleic acid.
GO:0034654	nucleobase-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0009890	negative regulation of biosynthetic process	Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances.
GO:0009892	negative regulation of metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0016070	RNA metabolic process	The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
GO:0010467	gene expression	The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, as well as translation and maturation for protein-coding genes.
GO:0010468	regulation of gene expression	Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).
GO:0009889	regulation of biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:2001141	regulation of RNA biosynthetic process	Any process that modulates the frequency, rate or extent of RNA biosynthetic process.
GO:0051252	regulation of RNA metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA.

100 Relations

Relationship	Parent Term . Identifier	Child Term . Identifier
is_a	GO:0045892	GO:0000122
is_a	GO:0045892	GO:0000410
is_a	GO:0045892	GO:0000433
is_a	GO:0045892	GO:0000434
is_a	GO:0045892	GO:0000437
part of	GO:0045892	GO:0001072
part of	GO:0045892	GO:0001073
is_a	GO:0045892	GO:0001081
part of	GO:0045892	GO:0001217
part of	GO:0045892	GO:0001217
part of	GO:0045892	GO:0001227
part of	GO:0045892	GO:0003714
is_a	GO:0045892	GO:0010620
is_a	GO:0045892	GO:0010621
is_a	GO:0045892	GO:0010688
is_a	GO:0045892	GO:0010689
is_a	GO:0045892	GO:0010690
is_a	GO:0045892	GO:0010691
is_a	GO:0045892	GO:0010944
is_a	GO:0045892	GO:0016479
is_a	GO:0045892	GO:0016480
part of	GO:0045892	GO:0016989
is_a	GO:0045892	GO:0017055
is_a	GO:0045892	GO:0031564
is_a	GO:0045892	GO:0032785
is_a	GO:0045892	GO:0034244
is_a	GO:0045892	GO:0045013
is_a	GO:0045892	GO:0045014
negatively regulates	GO:0006351	GO:0045892
negatively regulates	GO:0006351	GO:0045892

16 Synonyms

• Name: down regulation of transcription, DNA-dependent
• Type: synonym

• Name: down regulation of gene-specific transcription
• Type: synonym

• Name: down-regulation of transcription, DNA-dependent
• Type: synonym

• Name: down-regulation of gene-specific transcription
• Type: synonym

• Name: downregulation of transcription, DNA-dependent
• Type: synonym

• Name: downregulation of gene-specific transcription
• Type: synonym

• Name: inhibition of transcription, DNA-dependent
• Type: synonym

• Name: inhibition of gene-specific transcription
• Type: synonym

• Name: negative regulation of gene-specific transcription
• Type: synonym

• Name: negative regulation of cellular transcription, DNA-dependent
• Type: synonym

• Name: negative regulation of transcription, DNA-templated
• Type: synonym

• Name: negative regulation of transcription, DNA-dependent
• Type: synonym

• Name: GO:0016481
• Type: alt_id

• Name: transcription repressor activity
• Type: synonym

• Name: GO:0061021
• Type: alt_id

• Name: GO:0032582
• Type: alt_id