GO:0008150
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biological_process
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A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. |
GO:0003674
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molecular_function
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A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. |
GO:0005575
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cellular_component
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A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). |
GO:0005622
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intracellular anatomical structure
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A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm. |
GO:0110165
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cellular anatomical structure
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A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses. |
GO:0065007
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biological regulation
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Any process that modulates a measurable attribute of any biological process, quality or function. |
GO:0019222
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regulation of metabolic process
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Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. |
GO:0050794
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regulation of cellular process
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Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
GO:0060255
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regulation of macromolecule metabolic process
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Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. |
GO:0080090
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regulation of primary metabolic process
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Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. |
GO:0019219
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regulation of nucleobase-containing compound metabolic process
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Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. |
GO:0050789
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regulation of biological process
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Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. |
GO:0005488
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binding
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The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. |
GO:0003676
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nucleic acid binding
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Binding to a nucleic acid. |
GO:0043226
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organelle
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Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane. |
GO:0043229
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intracellular organelle
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Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. |
GO:0043228
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membraneless organelle
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Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes. |
GO:0043232
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intracellular membraneless organelle
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Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes. |
GO:0006357
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regulation of transcription by RNA polymerase II
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Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
GO:0010468
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regulation of gene expression
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Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). |
GO:0009889
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regulation of biosynthetic process
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Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances. |
GO:2001141
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regulation of RNA biosynthetic process
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Any process that modulates the frequency, rate or extent of RNA biosynthetic process. |
GO:0051252
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regulation of RNA metabolic process
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Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA. |
GO:0010556
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regulation of macromolecule biosynthetic process
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Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. |
GO:0006355
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regulation of DNA-templated transcription
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Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
GO:0000785
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chromatin
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The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome. |
GO:0005694
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chromosome
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A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. |
GO:1990837
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sequence-specific double-stranded DNA binding
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Binding to double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding. |
GO:0003677
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DNA binding
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Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
GO:0003690
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double-stranded DNA binding
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Binding to double-stranded DNA. |