WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0008219 cell death GO

Namespace  biological_process Obsolete  false
Description  Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

3 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0008219 cell death Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).

618 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0008219 GO:0001781
is_a GO:0008219 GO:0001783
part of GO:0008219 GO:0001836
is_a GO:0008219 GO:0001896
is_a GO:0008219 GO:0002342
is_a GO:0008219 GO:0002454
is_a GO:0008219 GO:0002516
regulates GO:0008219 GO:0002867
negatively regulates GO:0008219 GO:0002868
regulates GO:0008219 GO:0002868
regulates GO:0008219 GO:0002869
positively regulates GO:0008219 GO:0002869
regulates GO:0008219 GO:0002898
negatively regulates GO:0008219 GO:0002899
regulates GO:0008219 GO:0002899
regulates GO:0008219 GO:0002900
positively regulates GO:0008219 GO:0002900
is_a GO:0008219 GO:0002901
regulates GO:0008219 GO:0002902
negatively regulates GO:0008219 GO:0002903
regulates GO:0008219 GO:0002903
regulates GO:0008219 GO:0002904
positively regulates GO:0008219 GO:0002904
regulates GO:0008219 GO:0002905
negatively regulates GO:0008219 GO:0002906
regulates GO:0008219 GO:0002906
regulates GO:0008219 GO:0002907
positively regulates GO:0008219 GO:0002907
regulates GO:0008219 GO:0002908
regulates GO:0008219 GO:0002909

2 Synonyms

Name Type
necrosis synonym
accidental cell death synonym