WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0042088 T-helper 1 type immune response GO

Namespace  biological_process Obsolete  false
Description  An immune response which is associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis, and which is typically orchestrated by the production of particular cytokines by T-helper 1 cells, most notably interferon-gamma, IL-2, and lymphotoxin.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

7 Parents

Identifier Name Description
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0002376 immune system process Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
GO:0006955 immune response Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
GO:0002250 adaptive immune response An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory).
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus.
GO:0042088 T-helper 1 type immune response An immune response which is associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis, and which is typically orchestrated by the production of particular cytokines by T-helper 1 cells, most notably interferon-gamma, IL-2, and lymphotoxin.

26 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0042088 GO:0002296
regulates GO:0042088 GO:0002825
regulates GO:0042088 GO:0002825
negatively regulates GO:0042088 GO:0002826
negatively regulates GO:0042088 GO:0002826
regulates GO:0042088 GO:0002826
positively regulates GO:0042088 GO:0002827
positively regulates GO:0042088 GO:0002827
regulates GO:0042088 GO:0002827
part of GO:0042088 GO:0035744
is_a GO:0002460 GO:0042088
is_a GO:0006955 GO:0042088
is_a GO:0008150 GO:0042088
is_a GO:0002250 GO:0042088
is_a GO:0002376 GO:0042088
is_a GO:0050896 GO:0042088
part of GO:0042088 GO:0045063
regulates GO:0042088 GO:0045625
negatively regulates GO:0042088 GO:0045626
regulates GO:0042088 GO:0045626
regulates GO:0042088 GO:0045627
regulates GO:0042088 GO:2000554
negatively regulates GO:0042088 GO:2000555
regulates GO:0042088 GO:2000555
regulates GO:0042088 GO:2000556
positively regulates GO:0042088 GO:2000556

1 Synonyms

Name Type
Th1 immune response synonym