WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0003789 actin filament severing activity GO

Namespace  molecular_function Obsolete  false
Description  Binding to an actin subunit and promoting its dissociation from an actin filament by a local change in actin subunit conformation and orientation, and severing of filaments.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

17 Parents

Identifier Name Description
GO:0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0071840 cellular component organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0016043 cellular component organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0007010 cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0030029 actin filament-based process Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins.
GO:0030036 actin cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
GO:0005515 protein binding Binding to a protein.
GO:0044877 protein-containing complex binding Binding to a macromolecular complex.
GO:0008092 cytoskeletal protein binding Binding to a protein component of a cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton).
GO:0003779 actin binding Binding to monomeric or multimeric forms of actin, including actin filaments.
GO:0051015 actin filament binding Binding to an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
GO:0003789 actin filament severing activity Binding to an actin subunit and promoting its dissociation from an actin filament by a local change in actin subunit conformation and orientation, and severing of filaments.
GO:0140776 protein-containing complex destabilizing activity A molecular function that involves direct binding to one of the subunits of a protein-containing complex and promoting the dissociation of one or many subunits. This often happens by changing the conformation of the protein being bound, which decreases its affinity for the rest of the complex.

17 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0030036 GO:0003789
has part GO:0051015 GO:0003789
is_a GO:0140776 GO:0003789
part of GO:0009987 GO:0003789
part of GO:0030029 GO:0003789
is_a GO:0003674 GO:0003789
has part GO:0008092 GO:0003789
part of GO:0071840 GO:0003789
part of GO:0016043 GO:0003789
has part GO:0005515 GO:0003789
part of GO:0008150 GO:0003789
has part GO:0003779 GO:0003789
part of GO:0006996 GO:0003789
part of GO:0007010 GO:0003789
has part GO:0044877 GO:0003789
has part GO:0005488 GO:0003789
has part GO:0003674 GO:0003789

1 Synonyms

Name Type
actin depolymerizing activity synonym