WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity GO

Namespace  molecular_function Obsolete  false
Description  Catalysis of the cleavage of the C-O-P bond in the AP site created when DNA glycosylase removes a damaged base, involved in the DNA base excision repair pathway (BER).

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

8 Ontology Annotations

Annotation Extension Qualifier
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables

5 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0140640 catalytic activity, acting on a nucleic acid Catalytic activity that acts to modify a nucleic acid.
GO:0140097 catalytic activity, acting on DNA Catalytic activity that acts to modify DNA.
GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity Catalysis of the cleavage of the C-O-P bond in the AP site created when DNA glycosylase removes a damaged base, involved in the DNA base excision repair pathway (BER).

6 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0140097 GO:0003906
is_a GO:0003674 GO:0003906
is_a GO:0003824 GO:0003906
is_a GO:0140640 GO:0003906
is_a GO:0003906 GO:0052720
is_a GO:0003906 GO:0140078

8 Synonyms

Name Type
abasic deoxyendoribonuclease activity synonym
AP deoxyendoribonuclease activity synonym
apurinic deoxyendoribonuclease activity synonym
apurinic/apyrimidinic endodeoxyribonuclease activity synonym
apyrimidinic deoxyendoribonuclease activity synonym
deoxyribonuclease (apurinic or apyrimidinic) activity synonym
endonuclease VIII activity synonym
UV endonuclease synonym