WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0004197 cysteine-type endopeptidase activity GO

Namespace  molecular_function Obsolete  false
Description  Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

79 Ontology Annotations

Annotation Extension Qualifier
  enables
  enables
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  enables
  enables
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  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
has_input(WB:WBGene00006605) enables
  enables
  enables
  enables
  enables
  enables
  enables

8 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
GO:0140096 catalytic activity, acting on a protein Catalytic activity that acts to modify a protein.
GO:0008233 peptidase activity Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
GO:0004197 cysteine-type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
GO:0008234 cysteine-type peptidase activity Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
GO:0004175 endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.

14 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0004197 GO:0003923
is_a GO:0004175 GO:0004197
is_a GO:0008234 GO:0004197
is_a GO:0140096 GO:0004197
is_a GO:0016787 GO:0004197
is_a GO:0003824 GO:0004197
is_a GO:0008233 GO:0004197
is_a GO:0003674 GO:0004197
is_a GO:0004197 GO:0004198
negatively regulates GO:0004197 GO:0004869
negatively regulates GO:0004197 GO:0010859
is_a GO:0004197 GO:0070137
is_a GO:0004197 GO:0070139
positively regulates GO:0004197 GO:0140608

4 Synonyms

Name Type
caspase activity synonym
metacaspase activity synonym
lysosomal cysteine-type endopeptidase synonym
thiol endopeptidase activity synonym