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GO:0003674
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molecular_function
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A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. |
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GO:0003824
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catalytic activity
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Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. |
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GO:0016787
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hydrolase activity
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Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. |
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GO:0005488
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binding
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The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. |
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GO:0140096
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catalytic activity, acting on a protein
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Catalytic activity that acts to modify a protein. |
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GO:0005515
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protein binding
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Binding to a protein. |
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GO:0098772
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molecular function regulator activity
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A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition. |
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GO:0019899
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enzyme binding
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Binding to an enzyme, a protein with catalytic activity. |
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GO:0030234
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enzyme regulator activity
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Binds to and modulates the activity of an enzyme. |
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GO:0004857
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enzyme inhibitor activity
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Binds to and stops, prevents or reduces the activity of an enzyme. |
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GO:0140678
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molecular function inhibitor activity
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A molecular function regulator that inhibits or decreases the activity of its target via non-covalent binding that does not result in covalent modification to the target. |
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GO:0002020
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protease binding
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Binding to a protease or a peptidase. |
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GO:0008233
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peptidase activity
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Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid. |
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GO:0004197
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cysteine-type endopeptidase activity
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Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. |
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GO:0008234
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cysteine-type peptidase activity
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Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. |
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GO:0004175
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endopeptidase activity
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Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain. |
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GO:0030414
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peptidase inhibitor activity
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Binds to and stops, prevents or reduces the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds. |
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GO:0004866
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endopeptidase inhibitor activity
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Binds to and stops, prevents or reduces the activity of an endopeptidase. |
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GO:0061135
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endopeptidase regulator activity
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Binds to and modulates the activity of a peptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides. |
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GO:0061134
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peptidase regulator activity
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Binds to and modulates the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds. |
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GO:0004869
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cysteine-type endopeptidase inhibitor activity
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Binds to and stops, prevents or reduces the activity of a cysteine-type endopeptidase. |
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GO:0010859
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calcium-dependent cysteine-type endopeptidase inhibitor activity
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Binds to and stops, prevents or reduces the activity of a calcium-dependent cysteine-type endopeptidase, any enzyme that hydrolyzes peptide bonds in polypeptides by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile in a calcium-dependent manner. |
