WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0005035 death receptor activity GO

Namespace  molecular_function Obsolete  false
Description  Combining with an extracellular messenger (called a death ligand), and transmitting the signal from one side of the plasma membrane to the other to initiate apoptotic or necrotic cell death.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

9 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0060089 molecular transducer activity A compound molecular function in which an effector function is controlled by one or more regulatory components.
GO:0038023 signaling receptor activity Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
GO:0004888 transmembrane signaling receptor activity Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.
GO:0008219 cell death Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).
GO:0012501 programmed cell death A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.
GO:0005035 death receptor activity Combining with an extracellular messenger (called a death ligand), and transmitting the signal from one side of the plasma membrane to the other to initiate apoptotic or necrotic cell death.

12 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0005035 GO:0005031
is_a GO:0004888 GO:0005035
part of GO:0012501 GO:0005035
part of GO:0008150 GO:0005035
is_a GO:0038023 GO:0005035
is_a GO:0003674 GO:0005035
part of GO:0009987 GO:0005035
is_a GO:0060089 GO:0005035
part of GO:0008219 GO:0005035
is_a GO:0005035 GO:0036463
positively regulates GO:0005035 GO:0038177
positively regulates GO:0005035 GO:0038177

1 Synonyms

Name Type
apoptosis-activating receptor activity synonym