WormMine: GOTerm GO:0048019 receptor antagonist activity GO

• Namespace: molecular_function
• Obsolete: false
• Description: The activity of a gene product that interacts with a receptor to decrease the ability of the receptor agonist to bind and activate the receptor.

0 Cross References

1 Data Sets

• GO Annotation data set

1 Ontology

• Name: GO

11 Ontology Annotations

11 Parents

Identifier	Name	Description
GO:0003674	molecular_function	A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0005488	binding	The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0005515	protein binding	Binding to a protein.
GO:0098772	molecular function regulator activity	A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition.
GO:0060089	molecular transducer activity	A compound molecular function in which an effector function is controlled by one or more regulatory components.
GO:0005102	signaling receptor binding	Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
GO:0038023	signaling receptor activity	Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
GO:0030545	signaling receptor regulator activity	Binds to and modulates the activity of a receptor.
GO:0140678	molecular function inhibitor activity	A molecular function regulator that inhibits or decreases the activity of its target via non-covalent binding that does not result in covalent modification to the target.
GO:0048019	receptor antagonist activity	The activity of a gene product that interacts with a receptor to decrease the ability of the receptor agonist to bind and activate the receptor.
GO:0030547	signaling receptor inhibitor activity	Binds to and modulates the activity of a signaling receptor.

23 Relations

Relationship	Parent Term . Identifier	Child Term . Identifier
is_a	GO:0048019	GO:0005152
is_a	GO:0048019	GO:0030353
is_a	GO:0048019	GO:0038102
is_a	GO:0048019	GO:0045352
is_a	GO:0048019	GO:0045353
is_a	GO:0048019	GO:0046817
is_a	GO:0005102	GO:0048019
is_a	GO:0030547	GO:0048019
is_a	GO:0005515	GO:0048019
is_a	GO:0030545	GO:0048019
is_a	GO:0003674	GO:0048019
is_a	GO:0098772	GO:0048019
has part	GO:0003674	GO:0048019
negatively regulates	GO:0038023	GO:0048019
regulates	GO:0038023	GO:0048019
has part	GO:0005488	GO:0048019
regulates	GO:0003674	GO:0048019
is_a	GO:0005488	GO:0048019
is_a	GO:0140678	GO:0048019
negatively regulates	GO:0003674	GO:0048019
regulates	GO:0060089	GO:0048019
has part	GO:0005515	GO:0048019
negatively regulates	GO:0060089	GO:0048019

1 Synonyms

• Name: receptor ligand activity
• Type: synonym