WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0120115 Lsm2-8 complex GO

Namespace  cellular_component Obsolete  false
Description  A heteroheptameric, nuclear protein complex composed of Lsm2, Lsm3, Lsm4, Lsm5, Lsm6, Lsm7, and Lsm8, or orthologs thereof, that selectively binds to snRNAs, in particular U6 or U6atac snRNAs, and also to unspliced transcripts localized within the nucleus.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

4 Parents

Identifier Name Description
GO:0032991 protein-containing complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
GO:0005575 cellular_component A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).
GO:0120114 Sm-like protein family complex A protein complex containing members of the Like-Sm family of proteins, which includes both the Sm proteins and the Lsm proteins, and which generally form hexameric or heptameric ring structures which bind to RNA. While some of these ring complexes may form independently of RNA, many only form in association with their target RNA. In addition to Lsm-family proteins, many of these complexes contain additional protein members. Members of this family of complexes include the snRNPs which comprise the majority of the spliceosome. Others are involved in the 5' to 3' degradation pathways of mRNAs in the cytoplasm and of unspliced transcripts in the nucleus, as well as other diverse roles.
GO:0120115 Lsm2-8 complex A heteroheptameric, nuclear protein complex composed of Lsm2, Lsm3, Lsm4, Lsm5, Lsm6, Lsm7, and Lsm8, or orthologs thereof, that selectively binds to snRNAs, in particular U6 or U6atac snRNAs, and also to unspliced transcripts localized within the nucleus.

13 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
has part GO:0120115 GO:0005688
has part GO:0120115 GO:0046540
has part GO:0120115 GO:0071001
has part GO:0120115 GO:0071003
has part GO:0120115 GO:0071005
has part GO:0120115 GO:0071006
has part GO:0120115 GO:0071007
has part GO:0120115 GO:0071008
has part GO:0120115 GO:0071021
has part GO:0120115 GO:0071023
is_a GO:0120114 GO:0120115
is_a GO:0032991 GO:0120115
is_a GO:0005575 GO:0120115

0 Synonyms