WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0005790 smooth endoplasmic reticulum GO

Namespace  cellular_component Obsolete  false
Description  The smooth endoplasmic reticulum (smooth ER or SER) has no ribosomes attached to it. The smooth ER is the recipient of the proteins synthesized in the rough ER. Those proteins to be exported are passed to the Golgi complex, the resident proteins are returned to the rough ER and the lysosomal proteins after phosphorylation of their mannose residues are passed to the lysosomes. Glycosylation of the glycoproteins also continues. The smooth ER is the site of synthesis of lipids, including the phospholipids. The membranes of the smooth ER also contain enzymes that catalyze a series of reactions to detoxify both lipid-soluble drugs and harmful products of metabolism. Large quantities of certain compounds such as phenobarbital cause an increase in the amount of the smooth ER.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

12 Parents

Identifier Name Description
GO:0005737 cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
GO:0005575 cellular_component A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).
GO:0005622 intracellular anatomical structure A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm.
GO:0110165 cellular anatomical structure A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses.
GO:0043227 membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
GO:0043226 organelle Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
GO:0043229 intracellular organelle Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0043231 intracellular membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
GO:0012505 endomembrane system A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
GO:0016020 membrane A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.
GO:0005783 endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
GO:0005790 smooth endoplasmic reticulum The smooth endoplasmic reticulum (smooth ER or SER) has no ribosomes attached to it. The smooth ER is the recipient of the proteins synthesized in the rough ER. Those proteins to be exported are passed to the Golgi complex, the resident proteins are returned to the rough ER and the lysosomal proteins after phosphorylation of their mannose residues are passed to the lysosomes. Glycosylation of the glycoproteins also continues. The smooth ER is the site of synthesis of lipids, including the phospholipids. The membranes of the smooth ER also contain enzymes that catalyze a series of reactions to detoxify both lipid-soluble drugs and harmful products of metabolism. Large quantities of certain compounds such as phenobarbital cause an increase in the amount of the smooth ER.

28 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0005783 GO:0005790
has part GO:0110165 GO:0005790
part of GO:0012505 GO:0005790
has part GO:0005575 GO:0005790
has part GO:0016020 GO:0005790
is_a GO:0043231 GO:0005790
part of GO:0005575 GO:0005790
part of GO:0110165 GO:0005790
part of GO:0005622 GO:0005790
is_a GO:0110165 GO:0005790
is_a GO:0043229 GO:0005790
part of GO:0005737 GO:0005790
is_a GO:0043227 GO:0005790
is_a GO:0043226 GO:0005790
is_a GO:0005575 GO:0005790
part of GO:0005790 GO:0016029
part of GO:0005790 GO:0030868
part of GO:0005790 GO:0048238
part of GO:0005790 GO:0048238
occurs in GO:0005790 GO:0051563
occurs in GO:0005790 GO:0051563
occurs in GO:0005790 GO:0051564
occurs in GO:0005790 GO:0051565
part of GO:0005790 GO:0098557
part of GO:0005790 GO:0098558
part of GO:0005790 GO:0120082
part of GO:0005790 GO:1990039
part of GO:0005790 GO:1990040

2 Synonyms

Name Type
SER synonym
smooth ER synonym