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GO:0009987
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cellular process
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Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
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GO:0051179
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localization
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Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation. |
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GO:0008150
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biological_process
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A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. |
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GO:0051234
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establishment of localization
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Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. |
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GO:0006810
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transport
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The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein. |
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GO:0055085
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transmembrane transport
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The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. |
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GO:0005575
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cellular_component
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A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). |
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GO:0005622
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intracellular anatomical structure
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A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm. |
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GO:0110165
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cellular anatomical structure
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A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses. |
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GO:0051649
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establishment of localization in cell
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Any process, occurring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. |
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GO:0051641
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cellular localization
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A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane. |
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GO:0046907
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intracellular transport
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The directed movement of substances within a cell. |
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GO:0071705
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nitrogen compound transport
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The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
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GO:0033036
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macromolecule localization
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Any process in which a macromolecule is transported to, or maintained in, a specific location. |
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GO:0051668
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localization within membrane
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Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane. |
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GO:0008104
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protein localization
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Any process in which a protein is transported to, or maintained in, a specific location. |
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GO:0070727
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cellular macromolecule localization
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Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell. |
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GO:0015031
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protein transport
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The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
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GO:0045184
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establishment of protein localization
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The directed movement of a protein to a specific location. |
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GO:0006605
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protein targeting
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The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif. |
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GO:0006886
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intracellular protein transport
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The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. |
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GO:0072594
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establishment of protein localization to organelle
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The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle. |
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GO:0033365
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protein localization to organelle
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A process in which a protein is transported to, or maintained in, a location within an organelle. |
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GO:0006612
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protein targeting to membrane
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The process of directing proteins towards a membrane, usually using signals contained within the protein. |
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GO:0090150
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establishment of protein localization to membrane
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The directed movement of a protein to a specific location in a membrane. |
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GO:0072657
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protein localization to membrane
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A process in which a protein is transported to, or maintained in, a specific location in a membrane. |
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GO:0006613
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cotranslational protein targeting to membrane
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The targeting of proteins to a membrane that occurs during translation. The transport of most secretory proteins, particularly those with more than 100 amino acids, into the endoplasmic reticulum lumen occurs in this manner, as does the import of some proteins into mitochondria. |
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GO:0006614
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SRP-dependent cotranslational protein targeting to membrane
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The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane. |
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GO:0045047
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protein targeting to ER
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The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane. |
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GO:0072599
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establishment of protein localization to endoplasmic reticulum
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The directed movement of a protein to a specific location in the endoplasmic reticulum. |
