WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0045047 protein targeting to ER GO
Namespace  biological_process Obsolete  false
Description  The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane.
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0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

8 Ontology Annotations

Annotation Extension Qualifier
  involved_in
  involved_in
  involved_in
  involved_in
  involved_in
  involved_in
  involved_in
  involved_in

15 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0051179 localization Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0051234 establishment of localization Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.
GO:0051641 cellular localization A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane.
GO:0033036 macromolecule localization Any process in which a macromolecule is transported to, or maintained in, a specific location.
GO:0008104 protein localization Any process in which a protein is transported to, or maintained in, a specific location.
GO:0070727 cellular macromolecule localization Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
GO:0045184 establishment of protein localization The directed movement of a protein to a specific location.
GO:0006605 protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
GO:0072594 establishment of protein localization to organelle The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.
GO:0033365 protein localization to organelle A process in which a protein is transported to, or maintained in, a location within an organelle.
GO:0045047 protein targeting to ER The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane.
GO:0072599 establishment of protein localization to endoplasmic reticulum The directed movement of a protein to a specific location in the endoplasmic reticulum.
GO:0070972 protein localization to endoplasmic reticulum A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum.

22 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:0045047 GO:0006614
part of GO:0045047 GO:0006615
part of GO:0045047 GO:0006616
part of GO:0045047 GO:0006617
part of GO:0045047 GO:0006618
is_a GO:0045047 GO:0006620
part of GO:0045047 GO:0031203
part of GO:0045047 GO:0031204
is_a GO:0072599 GO:0045047
is_a GO:0006605 GO:0045047
is_a GO:0070727 GO:0045047
is_a GO:0045184 GO:0045047
is_a GO:0072594 GO:0045047
is_a GO:0008150 GO:0045047
is_a GO:0009987 GO:0045047
is_a GO:0070972 GO:0045047
is_a GO:0051234 GO:0045047
is_a GO:0051179 GO:0045047
is_a GO:0051641 GO:0045047
is_a GO:0033036 GO:0045047
is_a GO:0033365 GO:0045047
is_a GO:0008104 GO:0045047

3 Synonyms

Name Type
protein targeting to endoplasmic reticulum synonym
protein-endoplasmic reticulum targeting synonym
protein-ER targeting synonym