|
GO:0009987
|
cellular process
|
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
|
GO:0051179
|
localization
|
Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation. |
|
GO:0008150
|
biological_process
|
A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. |
|
GO:0051234
|
establishment of localization
|
Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. |
|
GO:0044238
|
primary metabolic process
|
The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. |
|
GO:0008152
|
metabolic process
|
A cellular process consisting of the biochemical pathways by which a living organism transforms chemical substances. This includes including anabolism (biosynthetic process) and catabolism (catabolic process). Metabolic processes includes the transformation of small molecules, as well macromolecular processes such as DNA repair and replication, protein synthesis and degradation. |
|
GO:0043170
|
macromolecule metabolic process
|
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. |
|
GO:0009058
|
biosynthetic process
|
A cellular process consisting of the biochemical pathways by which a living organism synthesizes chemical substances. This typically represents the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. |
|
GO:0019538
|
protein metabolic process
|
The chemical reactions and pathways involving a protein. Includes protein modification. |
|
GO:0009059
|
macromolecule biosynthetic process
|
The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. |
|
GO:0051641
|
cellular localization
|
A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane. |
|
GO:0010467
|
gene expression
|
The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, as well as translation and maturation for protein-coding genes. |
|
GO:0033036
|
macromolecule localization
|
Any process in which a macromolecule is transported to, or maintained in, a specific location. |
|
GO:0051668
|
localization within membrane
|
Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane. |
|
GO:0051604
|
protein maturation
|
Any process leading to the attainment of the full functional capacity of a protein. |
|
GO:0008104
|
protein localization
|
Any process in which a protein is transported to, or maintained in, a specific location. |
|
GO:0070727
|
cellular macromolecule localization
|
Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell. |
|
GO:0045184
|
establishment of protein localization
|
The directed movement of a protein to a specific location. |
|
GO:0006508
|
proteolysis
|
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. |
|
GO:0016485
|
protein processing
|
Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein. |
|
GO:0006465
|
signal peptide processing
|
The proteolytic removal of a signal peptide from a protein during or after transport to a specific location in the cell. |
|
GO:0006605
|
protein targeting
|
The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif. |
|
GO:0072594
|
establishment of protein localization to organelle
|
The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle. |
|
GO:0033365
|
protein localization to organelle
|
A process in which a protein is transported to, or maintained in, a location within an organelle. |
|
GO:0006612
|
protein targeting to membrane
|
The process of directing proteins towards a membrane, usually using signals contained within the protein. |
|
GO:0090150
|
establishment of protein localization to membrane
|
The directed movement of a protein to a specific location in a membrane. |
|
GO:0072657
|
protein localization to membrane
|
A process in which a protein is transported to, or maintained in, a specific location in a membrane. |
|
GO:0006613
|
cotranslational protein targeting to membrane
|
The targeting of proteins to a membrane that occurs during translation. The transport of most secretory proteins, particularly those with more than 100 amino acids, into the endoplasmic reticulum lumen occurs in this manner, as does the import of some proteins into mitochondria. |
|
GO:0006614
|
SRP-dependent cotranslational protein targeting to membrane
|
The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane. |
|
GO:0045047
|
protein targeting to ER
|
The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane. |
