WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0006620 post-translational protein targeting to endoplasmic reticulum membrane GO

Namespace  biological_process Obsolete  false
Description  The targeting of proteins to a membrane that occurs after their translation. Some secretory proteins exhibit posttranslational transport into the endoplasmic reticulum (ER) lumen: they are synthesized in their entirety on free cytosolic ribosomes and then released into the cytosol, where they are bound by chaperones which keep them in an unfolded state, and subsequently are translocated across the ER membrane.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

2 Ontology Annotations

Annotation Extension Qualifier
  involved_in
  involved_in

20 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0051179 localization Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0051234 establishment of localization Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.
GO:0051641 cellular localization A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane.
GO:0033036 macromolecule localization Any process in which a macromolecule is transported to, or maintained in, a specific location.
GO:0051668 localization within membrane Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane.
GO:0008104 protein localization Any process in which a protein is transported to, or maintained in, a specific location.
GO:0070727 cellular macromolecule localization Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
GO:0045184 establishment of protein localization The directed movement of a protein to a specific location.
GO:0006605 protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
GO:0072594 establishment of protein localization to organelle The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.
GO:0033365 protein localization to organelle A process in which a protein is transported to, or maintained in, a location within an organelle.
GO:0006612 protein targeting to membrane The process of directing proteins towards a membrane, usually using signals contained within the protein.
GO:0090150 establishment of protein localization to membrane The directed movement of a protein to a specific location in a membrane.
GO:0072657 protein localization to membrane A process in which a protein is transported to, or maintained in, a specific location in a membrane.
GO:0045047 protein targeting to ER The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane.
GO:0072599 establishment of protein localization to endoplasmic reticulum The directed movement of a protein to a specific location in the endoplasmic reticulum.
GO:0070972 protein localization to endoplasmic reticulum A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum.
GO:0006620 post-translational protein targeting to endoplasmic reticulum membrane The targeting of proteins to a membrane that occurs after their translation. Some secretory proteins exhibit posttranslational transport into the endoplasmic reticulum (ER) lumen: they are synthesized in their entirety on free cytosolic ribosomes and then released into the cytosol, where they are bound by chaperones which keep them in an unfolded state, and subsequently are translocated across the ER membrane.

21 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0045047 GO:0006620
is_a GO:0006612 GO:0006620
is_a GO:0070727 GO:0006620
is_a GO:0008150 GO:0006620
is_a GO:0070972 GO:0006620
is_a GO:0072657 GO:0006620
is_a GO:0072599 GO:0006620
is_a GO:0033365 GO:0006620
is_a GO:0033036 GO:0006620
is_a GO:0051234 GO:0006620
is_a GO:0051179 GO:0006620
is_a GO:0051641 GO:0006620
is_a GO:0072594 GO:0006620
is_a GO:0006605 GO:0006620
is_a GO:0045184 GO:0006620
is_a GO:0090150 GO:0006620
is_a GO:0051668 GO:0006620
is_a GO:0009987 GO:0006620
is_a GO:0008104 GO:0006620
part of GO:0006620 GO:0031203
part of GO:0006620 GO:0031204

6 Synonyms

Name Type
posttranslational protein targeting to ER membrane synonym
posttranslational protein targeting to endoplasmic reticulum membrane synonym
SRP-independent endoplasmic reticulum protein-membrane targeting synonym
posttranslational endoplasmic reticulum membrane targeting synonym
posttranslational protein endoplasmic reticulum membrane targeting synonym
posttranslational endoplasmic reticulum protein-membrane targeting synonym