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Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0007026 negative regulation of microtubule depolymerization GO
Namespace  biological_process Obsolete  false
Description  Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
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0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

4 Ontology Annotations

Annotation Extension Qualifier
  involved_in
  involved_in
  involved_in
  involved_in

38 Parents

Identifier Name Description
GO:0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0071840 cellular component organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0016043 cellular component organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0007017 microtubule-based process Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins.
GO:0007010 cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
GO:0000226 microtubule cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
GO:0043933 protein-containing complex organization Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex.
GO:0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0048523 negative regulation of cellular process Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0032984 protein-containing complex disassembly The disaggregation of a protein-containing macromolecular complex into its constituent components.
GO:0022411 cellular component disassembly A cellular process that results in the breakdown of a cellular component.
GO:0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0051129 negative regulation of cellular component organization Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0043244 regulation of protein-containing complex disassembly Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.
GO:0043242 negative regulation of protein-containing complex disassembly Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.
GO:0032886 regulation of microtubule-based process Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton.
GO:0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.
GO:0051493 regulation of cytoskeleton organization Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.
GO:0097435 supramolecular fiber organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure.
GO:0007019 microtubule depolymerization The removal of tubulin heterodimers from one or both ends of a microtubule.
GO:0051261 protein depolymerization The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein.
GO:0031109 microtubule polymerization or depolymerization Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule.
GO:1902904 negative regulation of supramolecular fiber organization Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization.
GO:0007026 negative regulation of microtubule depolymerization Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
GO:0031111 negative regulation of microtubule polymerization or depolymerization Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization.

57 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:1902904 GO:0007026
is_a GO:0031111 GO:0007026
negatively regulates GO:0007019 GO:0007026
negatively regulates GO:0007019 GO:0007026
is_a GO:0031114 GO:0007026
is_a GO:1901880 GO:0007026
is_a GO:0065007 GO:0007026
is_a GO:0048519 GO:0007026
negatively regulates GO:0043933 GO:0007026
is_a GO:0051493 GO:0007026
negatively regulates GO:0071840 GO:0007026
negatively regulates GO:0097435 GO:0007026
is_a GO:0051494 GO:0007026
regulates GO:0031109 GO:0007026
is_a GO:1902903 GO:0007026
regulates GO:0051261 GO:0007026
is_a GO:0031110 GO:0007026
negatively regulates GO:0016043 GO:0007026
regulates GO:0097435 GO:0007026
regulates GO:0022411 GO:0007026
negatively regulates GO:0031109 GO:0007026
is_a GO:0032886 GO:0007026
regulates GO:0043933 GO:0007026
is_a GO:0010639 GO:0007026
is_a GO:0070507 GO:0007026
negatively regulates GO:0008150 GO:0007026
regulates GO:0007010 GO:0007026
negatively regulates GO:0032984 GO:0007026
negatively regulates GO:0051261 GO:0007026
is_a GO:0033043 GO:0007026

8 Synonyms

Name Type
microtubule stabilization synonym
microtubule rescue synonym
negative regulation of microtubule disassembly synonym
negative regulation of microtubule catastrophe synonym
down-regulation of microtubule depolymerization synonym
down regulation of microtubule depolymerization synonym
inhibition of microtubule depolymerization synonym
downregulation of microtubule depolymerization synonym