WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0016248 channel inhibitor activity GO

Namespace  molecular_function Obsolete  false
Description  Binds to and stops, prevents, or reduces the activity of a channel.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

13 Parents

Identifier Name Description
GO:0022857 transmembrane transporter activity Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.
GO:0005215 transporter activity Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, accross or in between cells.
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0005515 protein binding Binding to a protein.
GO:0098772 molecular function regulator activity A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition.
GO:0015267 channel activity Enables the energy-independent facilitated diffusion of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
GO:0022803 passive transmembrane transporter activity Enables the transfer of a single solute from one side of a membrane to the other by a mechanism involving conformational change, either by facilitated diffusion or in a membrane potential dependent process if the solute is charged.
GO:0140678 molecular function inhibitor activity A molecular function regulator that inhibits or decreases the activity of its target via non-covalent binding that does not result in covalent modification to the target.
GO:0016247 channel regulator activity Binds to and modulates the activity of a channel. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel.
GO:0141108 transporter regulator activity Binds to and modulates the activity of a transporter.
GO:0016248 channel inhibitor activity Binds to and stops, prevents, or reduces the activity of a channel.
GO:0141110 transporter inhibitor activity Binds to and stops, prevents, or reduces the activity of a transporter.

27 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0016248 GO:0008200
negatively regulates GO:0015267 GO:0016248
is_a GO:0141110 GO:0016248
is_a GO:0016247 GO:0016248
regulates GO:0003674 GO:0016248
regulates GO:0005215 GO:0016248
has part GO:0003674 GO:0016248
has part GO:0005488 GO:0016248
is_a GO:0140678 GO:0016248
is_a GO:0003674 GO:0016248
negatively regulates GO:0005215 GO:0016248
negatively regulates GO:0003674 GO:0016248
has part GO:0005515 GO:0016248
is_a GO:0141108 GO:0016248
regulates GO:0015267 GO:0016248
negatively regulates GO:0022857 GO:0016248
negatively regulates GO:0022803 GO:0016248
regulates GO:0022803 GO:0016248
regulates GO:0022857 GO:0016248
is_a GO:0098772 GO:0016248
is_a GO:0016248 GO:0019855
is_a GO:0016248 GO:0019869
is_a GO:0016248 GO:0019870
is_a GO:0016248 GO:0019871
is_a GO:0016248 GO:0070320
is_a GO:0016248 GO:0140628
is_a GO:0016248 GO:0140629

0 Synonyms