WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0170060 microtubule destabilizing activity GO

Namespace  molecular_function Obsolete  false
Description  A protein-containing complex destabilizing activity that promotes microtubule catastrophe (transition from microtubule growth to microtubule shrinkage).

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

3 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0140776 protein-containing complex destabilizing activity A molecular function that involves direct binding to one of the subunits of a protein-containing complex and promoting the dissociation of one or many subunits. This often happens by changing the conformation of the protein being bound, which decreases its affinity for the rest of the complex.
GO:0170060 microtubule destabilizing activity A protein-containing complex destabilizing activity that promotes microtubule catastrophe (transition from microtubule growth to microtubule shrinkage).

3 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0170060 GO:0008568
is_a GO:0140776 GO:0170060
is_a GO:0003674 GO:0170060

2 Synonyms

Name Type
microtubule catastrophe inducing activity synonym
microtubule catastrophe promoting activity synonym